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GPR40 Activator 1

Cat. No.: DC42321

Chemical Structure

1309435-60-6

For research use only. We do not sell to patients.

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Field of application

GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1309435-60-6
Chemical Name:	GPR40 Activator 1
SMILES:	OC(C[C@H](C#CC)C(C=C1)=CC=C1OCC2=CC=C(CN3CCC4(C=CC5=C4C=CC=C5)CC3)S2)=O
Formula:	C₃₁H₃₁NO₃S
M.Wt:	497.65
Sotrage:	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Cat. No.	Product name	Field of application
DC44150	HWL-088	HWL-088 is a highly potent and orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC50 of 18.9 nM) with moderate PPARδ activity (EC50 of 570.9 nM) . HWL-088 improves glucose and lipid metabolism, and has anti-diabetic effects.
DC42321	GPR40 Activator 1	GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.
DC28968	TUG-424	TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity.

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