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TUG-424

Cat. No.: DC28968

Chemical Structure

1082058-99-8

For research use only. We do not sell to patients.

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Field of application

TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1082058-99-8
Formula:	C₁₈H₁₆O₂
M.Wt:	264.32
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC44150	HWL-088	HWL-088 is a highly potent and orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC50 of 18.9 nM) with moderate PPARδ activity (EC50 of 570.9 nM) . HWL-088 improves glucose and lipid metabolism, and has anti-diabetic effects.
DC42321	GPR40 Activator 1	GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes.
DC28968	TUG-424	TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.