Stigmasterol|cas 83-48-7|Supplied by DC Chem

Cas No.:	83-48-7
Chemical Name:	Stigmasterol
Synonyms:	Stigmasterol;3BETA-HYDROXY-24-ETHYL-5,22-CHOLESTADIENE;[3B-HYDROXY-24-ETHYL-D] ZZ-CHOLESTADIENE;5,22-STIGMASTADIEN-3-BETA-OL;5,22-CHOLESTADIEN-24B-ETHYL-3BETA-OL;5,22-CHOLESTADIEN-24BETA-ETHYL-3BETA-OL;(24S)-5,22-STIGMASTADIEN-3BETA-OL;STIGMASTERIN;Stigmasta-5,22-dien-3-ol,(3b,22E)-;STIGMASTEROL(AS);STIGMASTEROL(P) PrintBack;(3β,22E)-StigMasta-5,22-dien-3-ol;22-Dehydro-24-ethylcholesterol;24S-ethylcholest-5,22-dien-3β-ol;3β-Hydroxy-24-ethyl-5,22-cholestadiene;5,22-stigmastadien-3β-ol;5,22-StigMastadiene-3β-ol;Anti-stiffness factor;isofucosterol;PHYTOSTEROL;stigmasta-5,22-dien-3β-ol;Stigmastero;STIGMASTEROL (STIGMASTERIN);STIGMASTEROL(P);SULFISOXAZOLE;Stigmasta-5,22-dien-3beta-ol;Stigmasta-5;[ "Stigmasta-5", "22-dien-3-ol" ];110801;beta-Stigmasterol;D5-Stigmasterol;Stigmasterin; Phytosterol; beta-Stigmasterol; D5-Stigmasterol; 110801;(3β,22E)-Stigmasta-5,22-dien-3-ol (ACI);Stigmasta-5,22-dien-3β-ol (8CI);(24S)-24-Ethylcholesta-5,22-dien-3β-ol;(24S)-5,22-Stigmastadien-3β-ol;(24S)-Stigmast-5,22-dien-3β-ol;24-Ethyl-5,22-cholestadien-3β-ol;24β-Ethyl-5,22-cholestadien-3β-ol;MeSH ID: D013265;NSC 8095;Stigmasta-5,22(E)-dien-3β-ol;β-Stigmasterol;Δ5,22-Stigmastadien-3β-ol;Δ5-Stigmasterol
SMILES:	C[C@@]12[C@@H]([C@H](C)/C=C/[C@@H](CC)C(C)C)CC[C@H]1[C@@H]1CC=C3C[C@H](CC[C@]3(C)[C@H]1CC2)O
Formula:	C₂₉H₄₈O
M.Wt:	412.690829277039
Purity:	>98%, Standard References Grade
Sotrage:	4°C for 1 year, -20°C for more than 2 years

Description:

For the detailed information of Stigmasterol, the solubility of Stigmasterol in water, the solubility of Stigmasterol in DMSO, the solubility of Stigmasterol in PBS buffer, the animal experiment（test） (test) of Stigmasterol, the cell expriment (test) of Stigmasterol, the in vivo, in vitro and clinical trial test of Stigmasterol, the EC50, IC50,and Affinity of Stigmasterol,, please contact DC Chemicals.

Cat. No.	Product name	Field of application
DCG-002	β-Sitosterol	β-Sitosterol is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc.
DCD-042	Stigmasterol	Stigmasterol is an orally acitve, immunomodulatory agent with anti-inflammatory and neuroprotective effect, as well as able to cross the blood-brain barrier. Stigmasterol activates AMPK, which in turn inhibits NF-κB and NLRP3 signaling pathways, reduces microglia-mediated neuroinflammation, and alleviates cognitive impairment and Alzheimer's disease. Stigmasterol regulates M1/M2 polarization of microglia through the TLR4/ NF-κB pathway, thereby reducing neuropathic pain. Stigmasterol can be used for neurodegenerative diseases, inflammatory diseases, and pain management, among others.