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β-Sitosterol

  Cat. No.:  DCG-002   Featured
Chemical Structure
83-46-5
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More than 5000 active chemicals with high quality for research!
Field of application
β-Sitosterol is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc.
Cas No.: 83-46-5
Chemical Name: beta-Sitosterol
Synonyms: beta-Sitosterol;beta-sitosterol from soybean;beta-Sitosterol (1.03739);stigmast-5-en-3-beta-ol;Sitosterol;B-SITOSTEROL;A-PHYTOSTEROL;CINCHOL;22,23-DIHYDROSTIMASTEROL;22,23-DIHYDROSTIGMASTEROL;24-ALPHA-ETHYLCHOLESTEROL;24BETA-ETHYLCHOLESTEROL;beta-Sitosterol (contains Campesterol);24-Ethylcholest-5-en-3ß-ol;Bata-Sitosterol;SITOSTEROL, B-(P) (AHP Verified) PrintBack;SITOSTEROL, B-(RG);β-Sitosterol;α-Dihydrofucosterol;Synthetic;24-Ethylcholest-5-en-3beta-ol;alpha-Dihydrofucosterol;5-Stigmasten-3beta-ol;[ "" ];stigmast-5-en-3β-ol;β-sitosterin;植物甾醇;stigmast-5-en-3β-ol; β-sitosterin;Cupreol;Azuprostat;Triastonal;Quebrachol;Rhamnol;beta-Sitosterin;Nimbosterol;Harzol;Stigmast-5-en-3beta-ol;(3beta)-Stigmast-5-en-3-ol;Sito-Lande;(-)-beta-Sitosterol;24alpha-Ethylcholesterol;.beta.-Sitosterol;Angelicin (steroid);Sobatum;(24R)-Stigmast-5-en-3beta-ol;a-Dihydrofucosterol;(24R)-Ethylcholest-5-en-3beta-ol;.beta.-Sitosterin;Prostasal;NSC8096;Stigmast-5-en-3-ol, (3b)-;SITOSTEROL, BE;Pygeum Bark Africanum P.E;Phytosterol Granule;Dispersible Phytosterol;β-Sitosterol (purity>80%);22,23-Dihydrostigmasterol (purity>80%);β-Sitosterol (purity>98%);22,23-Dihydrostigmasterol (purity>98%);β-Sitosterol (purity>75%);22,23-Dihydrostigmasterol (purity>75%);Beta-Sitosterol (purity>80%);(3β)-Stigmast-5-en-3-ol (ACI);Nimbosterol (6CI);Stigmast-5-en-3β-ol (8CI);(-)-β-Sitosterol;(24R)-Ethylcholest-5-en-3β-ol;(24R)-Stigmast-5-en-3β-ol;24α-Ethylcholesterol;Angelicin;Betaprost;Inmunicin MAYMO;NSC 18173;NSC 49083;NSC 8096;Rhammol;SKF 14463;Stigmasterol, 22,23-dihydro-;α-Phytosterol;Δ5-Stigmasten-3β-ol;Pygoma Wood Extract;ConMedNP.2701;?-Sitosterin;ConMedNP.2702;SO_UY_002.1;19044-06-5;poriferast-5-en-3beta-ol;83-47-6;83-46-5;(3beta,24S)-stigmast-5-en-3-ol;24-Ethylcholest-5-en-3 beta-ol;beta-Sitosterol; Sitosterin;β-Sitosterol;(24R)-ethylcholest-5-en-3-beta-ol;Stigmast-5-en-3-ol; (3β,24R)-form;Stigmast 5-ene 3?-ol;beta-sitosterl;24?-Ethylcholesterol;gamma-Sitosterol;Clionasterol;24beta-ethyl-5-cholesten-3beta-ol;22,23-Dihydroporiferasterol;24S-ethylcholest-5-en-3beta-ol;80735-04-2;?-Dihydrofucosterol;?-Phytosterol;beta-dihydrofucosterol;24-Ethylcholesterol;Nettle Extract;14-((1S,4R)-4-ethyl-1,5-dimethylhexyl)(1S,5S,10S,11S,2R,14R,15R)-2,15-dimethyl tetracyclo[8.7.0.0<2,7>.0<11,15>]heptadec-7-en-5-ol;sitosterin;beta-Phytosterol;(24R)-Ethylcholest-5-en-3b-ol;DTXSID5022481;BIDD:PXR0121;SCHEMBL16105;Beta-sitosterol [WHO-DD];Stigmast-5-en-3-ol, (3beta)-;NCGC00142598-03;Prestwick1_000985;5-cholesten-24-ethyl-3-ol;(3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol;S0040;NCI60_041777;(3.BETA.)-STIGMAST-5-EN-3-OL;SPBio_002950;alpha-Dihydrofucosterol, 22,23-Dihydrostigmasterol;beta-Sitosterol, primary pharmaceutical reference standard;(3S,8S,9S,10R,13R,14S,1...
SMILES: C[C@@]12[C@@H]([C@H](C)CC[C@@H](CC)C(C)C)CC[C@H]1[C@@H]1CC=C3C[C@H](CC[C@]3(C)[C@H]1CC2)O
Formula: C29H50O
M.Wt: 414.706709384918
Purity: >98%, Standard References Grade
Sotrage: 4°C for 1 year, -20°C for more than 2 years
Description: For the detailed information of β-Sitosterol, the solubility of β-Sitosterol in water, the solubility of β-Sitosterol in DMSO, the solubility of β-Sitosterol in PBS buffer, the animal experiment(test) (test) of β-Sitosterol, the cell expriment (test) of β-Sitosterol, the in vivo, in vitro and clinical trial test of β-Sitosterol, the EC50, IC50,and Affinity of β-Sitosterol,, please contact DC Chemicals.
Cat. No. Product name Field of application
DCG-002 β-Sitosterol β-Sitosterol is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc.
DCD-042 Stigmasterol Stigmasterol is an orally acitve, immunomodulatory agent with anti-inflammatory and neuroprotective effect, as well as able to cross the blood-brain barrier. Stigmasterol activates AMPK, which in turn inhibits NF-κB and NLRP3 signaling pathways, reduces microglia-mediated neuroinflammation, and alleviates cognitive impairment and Alzheimer's disease. Stigmasterol regulates M1/M2 polarization of microglia through the TLR4/ NF-κB pathway, thereby reducing neuropathic pain. Stigmasterol can be used for neurodegenerative diseases, inflammatory diseases, and pain management, among others.
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