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DBPR116

  Cat. No.:  DC76611  
Chemical Structure
2131200-75-2
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More than 5000 active chemicals with high quality for research!
Field of application
DBPR116 is a prodrug of BPRMU191 with blood-brain barrier penetration capability. DBPR116 significantly improves the delivery of centrally targeted drugs. In combination with the antagonist Naltrexone, DBPR116 demonstrated superior safety and analgesic efficacy compared to morphine in various in vivo pharmacological studies, including thermal pain models, cancer pain models, constipation, sedation, psychological dependence, heart rate, and respiratory frequency. As a prodrug strategy for peripheral administration, DBPR116 effectively alleviates pain while reducing adverse effects, showing potential as a safer opioid analgesic.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 2131200-75-2
Chemical Name: DBPR116
SMILES: O=C(C1=CC=C(N2C(CSC2C3=CC=C(C=C3)F)=O)C(C)=C1)OCC
Formula: C19H18FNO3S
M.Wt: 359.41
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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