IL-17 modulator 4|CAS 2446803-65-0|DC Chemicals

Cas No.:	2446803-65-0
Chemical Name:	1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-
Synonyms:	1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-;IL-17 modulator 4
SMILES:	N1(C(C)C)C(C(N[C@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C2CC2)C2CC2)=O)=CC=N1
Formula:	C₂₇H₃₄N₆O₂
M.Wt:	474.60
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC72265	GDC-2394	GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1β with IC50s of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation.
DC47194	IL-4-inhibitor-1	IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM.
DC46954	CVN03650(IL-17 modulator 4)	IL-17 modulator 4 is a prodrug of IL-17 modulator 1. IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
DC46172	IL-17 modulator 3	IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
DC46037	LY3509754（IL-17A inhibitor 1）	IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells.

CVN03650(IL-17 modulator 4)