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SPH3127

Cat. No.: DC71814 Featured

Chemical Structure

1399849-02-5

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Field of application

SPH3127 (DRI 18) is a novel, highly potent, and orally active direct renin inhibitor (recombinant human-renin IC50=0.4 nM, human plasma renin activity IC50=0.45 nM). SPH3127 shows antihypertensive effect and can be used in essential hypertension research.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1399849-02-5
Chemical Name:	SPH3127
SMILES:	O=C(OC)NCCCN1N=C([C@H](N(C2CC2)C([C@H]3CNCCO3)=O)C)C4=CC=C(C)N=C41
Formula:	C₂₂H₃₂N₆O₄
M.Wt:	444.53
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC71814	SPH3127	SPH3127 (DRI 18) is a novel, highly potent, and orally active direct renin inhibitor (recombinant human-renin IC50=0.4 nM, human plasma renin activity IC50=0.45 nM). SPH3127 shows antihypertensive effect and can be used in essential hypertension research.
DC7699	VTP-27999	VTP-27999 is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases.
DCAPI1495	Aliskiren Hemifumarate	Aliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM.

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