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SYD5115 (SYD-5115, SYD 5115)

Cat. No.: DC73511

Chemical Structure

For research use only. We do not sell to patients.

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Field of application

SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:
Chemical Name:	SYD5115 (SYD-5115, SYD 5115)
SMILES:	O=C(O[C@H](C(C)(C)C)C)NC1=NC=C(N(C(C)=O)C2(C)C)C(C32CCC(F)(F)CC3)=N1
Formula:	C₂₂H₃₂F₂N₄O₃
M.Wt:	438.52

Cat. No.	Product name	Field of application
DC73510	Org 274179-0	Org 274179-0 is a highly potent, allosteric antagonist of the thyroid-stimulating hormone receptor (TSH receptor), inhibits bTSH-, hTSH- and M22-mediated CRE-luciferase transactivation in the CHO cell line.
DC40415	TSHR antagonist S37b	TSHR antagonist S37b is an enantiomer of TSHR antagonist S37a, shows only a minor effect for TSHR inhibition. TSHR antagonist S37b can be used for the research of thyroid function.
DC73511	SYD5115 (SYD-5115, SYD 5115)	SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively.

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