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TUG-499

Cat. No.: DC72535 Featured

Chemical Structure

1206629-08-4

For research use only. We do not sell to patients.

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Field of application

TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) (Free Fatty Acid Receptor) agonist with a pEC50 of 7.39. TUG-499 exhibits >100-fold selectivity over the related receptors FFA2, FFA3, and the nuclear receptor PPARγ and other diverse receptors, ion channels, and transporters. TUG-499 can be used for the research of type 2 diabetes.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1206629-08-4
Chemical Name:	TUG-499
SMILES:	O=C(O)CCC1=CC=C(C#CC2=CC(Cl)=NC(Cl)=C2)C=C1
Formula:	C₁₆H₁₁Cl₂NO₂
M.Wt:	320.17
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC72535	TUG-499	TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) (Free Fatty Acid Receptor) agonist with a pEC50 of 7.39. TUG-499 exhibits >100-fold selectivity over the related receptors FFA2, FFA3, and the nuclear receptor PPARγ and other diverse receptors, ion channels, and transporters. TUG-499 can be used for the research of type 2 diabetes.
DC72534	TUG-469	TUG-469 is a selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 value of 19 nM. TUG-469 is >200-fold selective for FFA1 over FFA4. TUG-469 significantly improves glucose tolerance in pre-diabetic mice. TUG-469 can be used for the research of diabetes.

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