WX-UK1|CAS 220355-63-5|DC Chemicals

Cas No.:	220355-63-5
Chemical Name:	WX-UK1
Synonyms:	UKI-1
SMILES:	O=C(OCC)N1CCN(C(=O)C(CC2C=C(C(=N)N)C=CC=2)NS(=O)(C2C(C(C)C)=CC(C(C)C)=CC=2C(C)C)=O)CC1
Formula:	C₃₂H₄₇N₅O₅S
M.Wt:	613.8111
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC11078	Cenupatide	Cenupatide is an urokinase plasminogen activator receptor (uPAR) inhibitor drug candidate. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of streptozotocin (STZ)-induced diabetes. Cenupati
DC74593	ACT001(DMAMCL)	ACT001(DMAMCL, dimethylaminomicheliolide) is a PAI-1 inhibitor and exerts antitumor effects on neuroblastoma (NB) both in vitro and in vivo. It also exerts synergistic effects in combination with cisplatin through the inhibition of the PAI-1/PI3K/AKT pathway.
DC73778	WX-340	WX-340 is a highly specific and selective, peptidic cyclic competitive inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 12 and 170 nM for human and mouse uPA, respectively, inhibit 10 Units of human uPA with IC50 of 90 nM.
DC73777	WX-293	WX-293 is a highly selective small-molecule inhibitor of urokinase-type plasminogen activator (uPA) with Ki of 2.4 uM.
DC73776	IPR-3011	IPR3011 is a small-molecule uPAR-uPA protein-protein interaction inhibitor with Ki of 2.4 uM.
DC70093	WX-UK1	WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth.
DC50259	Geodin	Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1).