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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Endogenous Metabolite

Endogenous Metabolite

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Cat. No. Product Name Field of Application Chemical Structure
DC48442 L-Tryptophan-13C11,15N2
L-Tryptophan-13C11,15N2 (Tryptophan-13C11,15N2) is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.
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DC48245 3-Oxo-7-hydroxychol-4-enoic acid
3-Oxo-7-hydroxychol-4-enoic acid is an endogenous metabolite. 3-Oxo-7-hydroxychol-4-enoic acid may be an important indicator of a poor prognosis in hepatobiliary disease.
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DC48244 Delta-12-Prostaglandin J2
Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation.
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DC48243 C20 Ceramide
C20 Ceramide is a natural 20:0 ceramide that is abundant in the brain.
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DC48242 ω-Muricholic Acid
ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.
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DC48241 p-Cresyl sulfate
p-Cresyl Sulfate, a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver, existed in the blood of patients with chronic kidney disease (CKD).
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DC48240 Pregnanediol 3-glucuronide
Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species.
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DC48239 12-OxoETE
12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence.
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DC48238 10(S),17(S)-DiHDHA
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities.
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DC48237 Dihomo-γ-Linolenic acid methyl ester
Dihomo-γ-Linolenic acid is an n-6 polyunsaturated fatty acid that is mainly metabolized to an anti-inflammatory eicosanoid, prostaglandin (PG) E1, via the cyclooxygenase (COX) pathway. Anti-inflammatory and anti-proliferative effects.
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DC48236 4β-Hydroxycholesterol
4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation.
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DC48067 1,7-Dimethyluric acid
1,7-Dimethyluric acid is the metabolite of caffeine.
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DC48057 AFMK
AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. AFMK is a poorer scavenger. The pKa of AFMK at physiological pH is 8.7. Antioxidant capacity. AFMK improves the anti-tumor effect of Gemcitabine in PANC-1 cells through the modulation of apoptotic pathway.
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DC47959 Lignoceric acid
Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research.
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DC47895 Sphinganine 1-phosphate
Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes.
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DC47880 trans-Urocanic acid
trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function.
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DC28860 Streptolysin O
Streptolysin O, a group A streptococcal toxin, is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin. Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state .
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DC29170 L-Methionine sulfoxide Featured
L-Methionine sulfoxide (H-Met(O)-OH), a metabolite of Methionine, induces M1/classical macrophage polarization, and modulates oxidative stress and purinergic signaling parameters.
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DC47664 Indole-3-acetaldehyde
Indole-3-acetaldehyde inhibits Escherichia coli O157:H7 biofilm formation.
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DC47665 4-Hydroxytryptamine creatinine sulfate
4-Hydroxytryptamine creatinine sulfate, a tryptamine derivative, is a neurotransmitter agonist.
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DC47214 Phosphoribosyl pyrophosphate pentasodium
Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP.
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DC47141 Triiodothyronine sulfate
Triiodothyronine sulfate is the main metabolite of thyroid hormone triiodothyronine (T3). Triiodothyronine is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
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DC47116 Deutarserine
Deutarserine is a deuterium modified analog of endogenous D-serine (CTP 692), which is used in the research of adults with schizophrenia.
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DC47095 Larsucosterol sodium
Larsucosterol sodium is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.
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DC47040 Larsucosterol
Larsucosterol is a cholesterol metabolite from the nuclei of normal human liver tissues, epigenetically regulates the transcription of proteins and enzymes involved in lipid synthesis, inflammation, and apoptosis.
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DC47034 Ebaresdax
Ebaresdax can inhibit peroxynitrite oxidation derived by SIN-1 and peroxynitrite mediated Cytotoxicity with IC50s of 3.7±0.80 and 0.13±0.02 uM, respectively.
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DC47032 3-Oxo-4,6-choladien-24-oic acid
3-Oxo-4,6-choladien-24-oic acid is an endogenous metabolite. 3-Oxo-4,6-choladien-24-oic acid exsists in the urine of patients with hepatobiliary disease.
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DC47031 2,8-Dihydroxyadenine
2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones. 2,8-Dihydroxyadenine can be used to diagnose adenine phosphoribosyltransferase (APRT) deficiency.
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DC46531 Folitixorin
Folitixorin (5,10-methylenetetrahydrofolate) is a cofactor and an analog of leucovorin. Folitixorin is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research.
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DC46483 Angiotensinogen (1-14), human TFA
Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides.
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