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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC37313 Benzyl lactate
Benzyl lactate is a biochemical.
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DC37241 Myristyl glycol
Myristyl glycol is a type of glycol.
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DC37038 Tafluprost acid
Tafluprost acid is a selective agonist at the prostaglandin F receptor, increasing outflow of aqueous fluid from the eyes and thus lowering intraocular pressure.
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DC36906 IDO-IN-3
IDO-IN-3 is an inhibitor of indoleamine-2,3-dioxygenase 1.
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DC36852 Mahanimbine
Mahanimbine is a major carbazole alkaloid from Murraya koenigii (curry leaves) that may alleviate development of HFD-induced metabolic alterations.
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DC36797 WEHI-539 HCl
WEHI-539 has high affinity (IC50=1.1 nM) and selectivity for BCL-XL and potently kills cells by selectively antagonizing its prosurvival activity. It has more than a 400-fold higher affinity for BCL-XL versus other prosurvival BCL-2 family members.
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DC36422 3-hydroxy Darifenacin
3-hydroxy Darifenacin is a metabolite of darifenacin. It is an antagonist of M1-5 muscarinic receptors.
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DC36352 Feglymycin
Feglymycin is a 13-amino acid peptide that has antibacterial and antiviral activities. It is active against Gram-positive bacteria and inhibits HIV viral replication.
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DC36328 CAY10737
CAY10737 is a turn-on fluorescent probe for the detection of carbon monoxide (CO). It is selective for CO over a variety of anions, amino acids, amines, biothiols, and reactive species. In the presence of palladium (Pd) and CO, CAY10737 undergoes the Pd0-mediated Tsuji-Trost reaction to release a fluorescent compound that has absorption and emission maxima of 678/714 nm, respectively. This fluorescence can be used to detect CO production in vitro and in vivo.
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DC36231 Pasiniazid
Pasiniazid is a biochemical used in the treatment of tuberculosis
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DC36146 AI3-63042
Gallein is a Gβγ subunit signalling inhibitor which has been shown to inhibit metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand.
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DC36114 AMBMP hydrochloride
AMBMP hydrochloride is a Wnt canonical signaling activator and tubulin polymerization inhibitor.
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DC36061 APHS
APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.
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DC35919 m-PEG8-(CH2)12-phosphonic acid ethyl ester
m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG Linker.
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DC35913 m-PEG8-(CH2)12-phosphonic acid
m-PEG8-(CH2)12-phosphonic acid is a PEG Linker.
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DC35910 m-PEG9-phosphonic acid
m-PEG9-phosphonic acid is a PEG Linker.
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DC35885 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation that possesses a cleavable peptide sequence. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35884 Azido-PEG4-Ala-Ala-Asn(Trt)-PAB
Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a PEG derivative conjugated with a peptide via an amide bond. The azide group on the PEG end enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35883 Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35882 Azido-PEG5-Ala-Ala-Asn-PAB
Azido-PEG5-Ala-Ala-Asn-PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation. The Azido group is very reactive toward DBCO, BCN or other Alkyne groups for click chemistry. The hydrophilic PEG spacer increases the solubility in aqueous media.
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DC35881 Fmoc-PEG4-Ala-Ala-Asn-PAB
Fmoc-PEG4-Ala-Ala-Asn-PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35880 Azido-PEG3-Val-Cit-PAB-PNP
Azido-PEG3-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will be release only in the cell. The Azido group will react with DBCO, BCN or other Alkyne group through click chemistry, PEG spacer increases aqueous solubility.
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DC35879 Azido-PEG4-Val-Cit-PAB-OH
Azido-PEG4-Val-Cit-PAB-OH is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry.
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DC35878 Azido-PEG3-Val-Cit-PAB-OH
Azido-PEG3-Val-Cit-PAB-OH is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit croup will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry.
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DC35877 Mal-amido-PEG2-Val-Cit-PAB-PNP
Mal-amido-PEG2-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35876 Mal-PEG4-Val-Cit-PAB-PNP
Mal-PEG4-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released in the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35875 Mal-PEG4-Val-Cit-PAB-OH
Mal-PEG4-Val-Cit-PAB-OH is a linker for Antibody-Drug-Conjugation (ADC). The Val-Cit group will specifically be cleaved by catepsin B. Because this enzyme is only present in the lysosome, the ADC payload will only be released within the cell. The Azido group will react with DBCO, BCN or other Alkyne groups through click chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35867 N-Mal-N-bis(PEG2-t-butyl ester)
N-Mal-N-bis(PEG2-t-butyl ester) is a branched PEG derivative with a terminal maleimide group and two terminal t-butyl esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.
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DC35863 N-Mal-N-bis(PEG4-NHS ester)
N-Mal-N-bis(PEG4-NHS ester) is a branched PEG derivative with a terminal maleimide group and two terminal NHS esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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DC35861 N-Mal-N-bis(PEG4-acid)
N-Mal-N-bis(PEG4-acid) is a branched PEG derivative with two terminal carboxylic acids and a maleimide group. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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