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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC22168 MU1210
MU1210 (MU-1210) is a potent and highly selective inhibitor of cdc-like kinases (CLKs) with IC50 of 51 nM (cellular BRET for CLK1).
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DC20468 Mtphagy Dye
Mtphagy Dye is a small-molecule fluorescent probe for visualizing mitophagy.
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DC21353 MSN-125
MSN-125 (MSN 125, MSN125) is a small molecule Bax inhibitor that inhibits Bax/Bak oligomerization and prevents mitochondrial outer membrane permeabilization (MOMP) with IC50 of 4 uM.
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DC21352 MSC 1094308
MSC1094308 (MSC 1094308) is a reversible, allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B with IC50 of 7.2 and 0.71 uM, respectively.
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DC23316 MS7972
MS7972 is a small molecules that blocks p53 and CREB binding protein (CBP) association.
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DC21350 MS4077
MS4077 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=3 nM).
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DC21349 MS-377
MS-377 is a potent, selective sigma-1 receptor ligand with Kd of 15.2 nM, showed anti-phencyclidine (PCP), anti-dopaminergic and anti-serotonergic activities.
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DC21346 MS012
MS012 is a potent and selective inhibitor of G9a-Like Protein (GLP) lysine methyltransferase with IC50 of 7 nM, shows >30-fold selectivity for GLP over G9a and other methyltransferases..
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DC23898 MRT-83 hydrochloride
MRT-83 hydrochloride is a potent Smoothened antagonist that blocks Hedgehog (Hh) signaling in various assays with IC50 of 10 nM.
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DC21344 MRT 199665
MRT 199665 is a potent salt-inducible kinases (SIKs) inhibitor with IC50 of 110, 12, 43 nM for SIK1,2,3 respectively.
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DC22165 MRS4478
MRS4478 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 269 nM, does not display extensive off-target interactions with biogenic amine receptors..
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DC22164 MRS4458
MRS4458 is a potent, highly specific amtagonist of P2Y14 receptor with IC50 of 169 nM, does not display extensive off-target interactions with biogenic amine receptors..
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DC12260 MRS1177
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
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DC23740 MRS 2485
MRS 2485 is a potent, irreversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity..
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DC23733 MRS 2481
MRS 2481 is a potent, reversible Aβ42 neurotoxicity inhibitor with ID50 of 500 nM, potently blocks the Aβ calcium channel and protects neurons from Aβ toxicity.
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DC23471 MRS 2179 tetrasodium
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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DC23483 MRS 2179
MRS 2179 is a potent, selective, competitive P2Y1 receptor antagonist with Kb of 100 nM.
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DC23711 MRL20
MRL20 is a novel synthetic PPARγ ligand and orthosteric agonist with canonical LBP binding affinity of 2 nM.
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DC21343 MRL-1237
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
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DC21923 MRK-A
MRK-A is a potent, highly selective, brain penetrant inhibitor of mutant IDH1 with IC50 of 5 nM, displays a 10,000-fold mutant to wildtype selectivity ratio.
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DC23616 MRK-696
MRK-696 is a non-selective benzodiazepine receptor partial agonist..
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DC23655 MRK-623
MRK-623 is a potent, α2/α3 subunit functionally selectiviie GABAA receptor agonist..
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DC23877 MRK-560
MRK-560 is a potent, brain-penetrant and orally bioavailable γ-secretase inhibitor that inhibits proteolytic cleavage of APP over the Notch pathway.
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DC20465 mPGES1-IN-17d
mPGES1-IN-17d is a potent, selective mPGES-1 inhibitor with enzyme IC50 of 8 nM, A549 cell IC50 of 16.24 nM, human whole blood IC50 of 249.9 nM.
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DC20464 mPGES1-IN-16
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM.
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DC22554 MP-A08
MP-A08 is a first-in-class, highly selective, ATP competitive sphingosine kinase (SphK) inhibitor (Ki of 6.9/27 uM for SK2/SK1).
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DCAPI1572 Moxonidine hydrochloride
Moxonidine hydrochloride
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DCAPI1331 Moxonidine
Moxonidine
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DC12485 Mosedipimod
Mosedipimod (EC-18, 1-palmitoyl-2-linoleoyl-3-acetylglycerol) is a synthetic monoacetyldiaglyceride that stimulates T cell production of IL-2, IL-4, IL-12, IFN-γ, and GM-CSF in vitro.
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DC8931 Mosapride
Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
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