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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC5477 | vuf10148 |
Potent H4R ligand
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| DCC5476 | Vuf10132 |
Novel full inverse agonist at CXCR3 N3.35A
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| DCC5475 | Vuf 5681 Dihydrobromide |
Potent histamine H3 receptor silent antagonist
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| DCC5474 | Vu6027459 |
First-in-class selective mGlu7 positive allosteric modulator (PAM), displaying CNS penetration in both mice (Kp = 2.74) and rats (Kp= 4.78)
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| DCC5473 | Vu6017587 |
Novel selective mGlu3 NAM, showing efficacy in tail suspension, elevating zero maze and marble burying, suggesting selective inhibition of mGlu3 affords anxiolytic-like and antidepressant-like phenotypes in mice
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| DCC5472 | Vu6013429 |
Novel PAM of Group III (mGlu4/6/7/8) mGlu receptors
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| DCC5471 | Vu6009833 |
Novel CNS penetrant pan-muscarinic antagonist
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| DCC5470 | Vu6009453 |
Novel M4 positive allosteric modulator (PAM)
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| DCC5469 | Vu6008555 |
Novel Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)
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| DCC5468 | Vu6007705 |
Novel Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM)
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| DCC5467 | Vu6004909 |
Novel potent and highly selective mGlu1 PAM (22nM), reducing striatal DA release in vivo and displaying antipsychotic efficacy
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| DCC5466 | Vu6001192 |
Novel selective negative allosteric modulator (NAM) of metabotropic glutamate receptor subtype 2
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| DCC5465 | vu573 Hydrochloride |
Novel modulator of mammalian inward rectifying potassium (Kir) channels
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| DCC5464 | Vu0487836 |
Novel cyclooxygenase-1 (COX-1)-selective inhibitor
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| DCC5463 | Vu0486321 |
mGlu1 positive allosteric modulator (PAM)
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| DCC5462 | Vu0477886 |
Novel potent mGlu4 PAM with an attractive DMPK profile, and robust efficacy in preclinical Parkinsons disease model, haloperidol-induced catalepsy (HIC)
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| DCC5461 | vu0463841 |
Potent and selective mGlu5 negative allosteric modulator (NAM)
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| DCC5460 | Vu0462054 |
Novel potent and selective metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM)
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| DCC5459 | Vu0453379 |
Novel, CNS Penetrant Glucagon-Like Peptide 1 Receptor (GLP-1R) Positive Allosteric Modulator (PAM)
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| DCC5458 | vu0452865 |
Selective orthosteric M1 antagonist
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| DCC5457 | vu0448350-1 |
Highly selective muscarinic M1 PAM
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| DCC5456 | Vu0431316 |
Novel negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety
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| DCC5455 | Vu0415374 |
Novel mGlu4 positive allosteric modulator (PAM)
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| DCC5454 | Vu0415371 |
Novel M4 muscarinic acetylcholine receptor modulator
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| DCC5453 | vu0415248 |
Highly M1-selective antagonist
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| DCC5452 | Vu0413144 |
Allosteric modulator of the M2/5 muscarinic acetylcholine receptor
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| DCC5451 | Vu0410150 |
Novel positive allosteric modulator (PAM) of mGlu4
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| DCC5450 | Vu0409775 |
Muscarinic antagonist; inhibiting ACh-induced Ca(2+) responses at rat M(1-5) receptor subtypes
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| DCC5449 | Vu0404251 |
Highly potent non-MPEP site metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (PAM)
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| DCC5448 | vu0403602 |
Novel Positive Allosteric Modulator (PAM) of the Metabotropic Glutamate Receptor 5 (mGlu5)
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