Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Novel CDK6 inhibitor

Novel dose-dependent inhibitor of TNF-α-induced NF-κB activation

Potent Ebolavirus (EBOV) Inhibitor

Novel effective immune check point inhibitor (ICI) against the suppression of T-cell activation, proliferation, and tumor cell eradication.

Novel SIRT1 inhibitor

Novel SIRT1 inhibitor

Novel SIRT1 inhibitor

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Potent and selective agonist of peroxisome proliferator activated receptors-α (PPAR-α)

Novel TNF-α inhibitor

Novel potent small molecule lligand of miR-21, binding to the major groove of miR-21 hairpin conformation

Novel effective immune checkpoint inhibitor (ICI) against the suppression of T-cell activation, proliferation, and tumor cell eradication.

Novel TNF-α inhibitor

Novel Nef Protein Inhibitor; Anti-HIV

Novel blocker of AKT1-FAK interaction, reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation

Potent VEGFR-2 inhibitor

Novel antagonist for mLST8

The first nonpeptidic inhibitor of ovarian cancer cells growth targeting human thymidylate synthase (hTS)

Growth promotant, acting as a ß-AR (ß-Adrenergic) agonist

Atypical analgesic agent for the amelioration of severe and chronic pain

Fluorogenic peptide substrate for a direct fluorometric assay of urokinase, tissue-type plasminogen activator, trypsin and thrombin

Novel Potent and Orally Bioavailable Hypoxia-Inducible Factor 2α (HIF-2α) Agonist

Novel inhibitor of pro-HGF activation

Novel daul inhibitor of GSK-3β (IC 50 = 71 nM) and DYRK1A (IC 50 = 103 nM) with good blood-brain barrier penetrability, inhibiting hyperphosphorylation of tau protein in okadaic acid (OKA)-induced SH-SY5Y cells

Site specific inhibitor of tissue transglutaminase

Novel potent HDAC inhibitor with IC50 values for class I HDACs 1, 2, and 3 below 4 nM, and IC50 for HDAC6 at 6 nM.

ZDHHC (zinc finger Asp-His-His-Cys) substrate peptide, a 15-mer peptide sequence from KRas4a plus two tryptophan residues

Potassium channel opener

Vascular targeting agent (VTA)