Tyrosinase-IN-17 (Compound 5b) is a lipophilic, skin-permeable, and non-cytotoxic Tyrosinase inhibitor (pIC50=4.99). Tyrosinase-IN-17 can be used for research on melanin-related diseases, such as melanoma, melanogenesis, etc.

Dual dopamine D2 and muscarinic M1 receptor ligand with putative antipsychotic and pro-cognitive potential

VU0366248 is a mGlu5 negative allosteric modulator.

WAY-649123 is an active molecule.

WAY-325811 is an active molecule.

WAY-616296 is an active molecule.

WAY-328127 is an active molecule.

WAY-215718 is an active molecule.

WAY-639872 is an active molecule.

BAY 1892005 is a small molecule that modulate mutant p53 condensation and nuclear accumulation, binds covalently to mutant p53R175H and p53Y220C and shows stabilization of p53WT and p53Y220C, exhibits anti-proliferative activity in a set of cell lines wit

Anti-inflammatory agent 63 is an anti-inflammatory agent that shows optimal inhibitory activity (EC50 = 5.33±0.57 μM) against the production of nitric oxide (NO) induced by lipopolysaccharide (LPS) in RAW264.7 cells.

WAY-221060-A is an active molecule.

Nurr1 agonist 8 (compound 111) is a Nurr1 agonist with an EC50 value of 0.09 μM.

Nurr1 agonist 7 (compound 110) is a Nurr1 agonist with an EC50 value of 0.12 μM.

WAY-607695 is an active molecule.

WAY-620521 is an active molecule.

WAY-639228-A is an active molecule.

WAY-324572 is an active molecule.

WAY-660222 is an active molecule.

WAY-659873 is an active molecule.

WAY-658675 is an active molecule.

Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM.

WAY-608106 is an active molecule.

WAY-354574 is an active molecule targeting deacetylase (Sirtuin) for the study of Huntington's disease (HD).

WAY-621924 is an active molecule.

WAY-604603 is an active molecule.

WAY-637940 is an active molecule.

WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively.

N-Cyclopropyl-4-iodobenzamide is an active molecule.

WAY-309236 is an active molecule for the study of amyloid diseases and synucleinopathies.