Novel type I Interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, binding preferentially to unphosphorylated IRAK4

Novel inhibitor of the heat shock protein 70 (Hsp70) with anti-proliferative activity in breast and prostate cancer cells

Novel human flap endonuclease 1 (FEN1) inhibitor with in vitro inhibition of flap cleavage activity as well as cytotoxic activity against a colon cancer cell line, DLD-1

Novel apoptosis inducer, significantly inhibiting tumor growth in the xenograft model

Peripheral Selective CB1 Receptor Antagonist

Novel irriversable serine hydrolases inhibitor

Novel potent inhibitor of Mpro

Covalent dual inhibitor of DPAP1 and DPAP3

Covalent dual inhibitor of DPAP1 and DPAP3

Novel dose-dependent inhibitor of ABHD6

Negative control of JCP174

JCP174 analog used for affinity purification of labeled targets

Novel dose-dependent inhibitor of ABHD6

Novel RORα activator, diminishing diethylnitrosamine-induced acute liver injury and repressing transcriptional expression of APPs such as CXCL1 and LCN2 in mice

Metabolite of JBSNF-000088

Natural anti-inflammatory agent, showing potential for the treatment of inflammatory bowel disease (IBD)

Inhibitor of renal transporters OAT1 and OAT3; Antihepatitis agent as a substrate for intestinal PEPT1

Natural radical scavenger, inhibiting L-glutamate toxicity in neuronal hybridoma N18-RE-105 cells

Natural Inhibitor for Protein−Protein Interaction of the Homodimer of Proteasome Assembly Factor 3

Potent inhibitor of the proliferation of PC3 prostate carcinoma cells

Natural naphthyridine alkaloid

Novel Inhibitor of Jumonji AT-Rich Interactive Domain 1B (JARID1B) Histone Demethylase

Novel mitophagy inducer with therapeutic potential for Parkinson's disease, acting as light chain 3 (LC3) interactors, similar to cardiolipin or ceramide, triggering mitophagy via Pink1/Parkin

Novel fluorogenic yellow fluorescent dye for use in self-labeling tag systems

Novel anti-triple-negative breast cancer (anti-TNBC) agent with a high selectivity against BC cells over normal human cells, downregulating phosphatidylinositide 3-kinase (PI3K)/Akt pathway by suppressing protein-tyrosine phosphatase 1B (PTP1B) expression

Novel positive allosteric modulator of AMPA receptor

Novel potent JAK1/3 inhibitor, targeting JAK3 and JAK1 with IC 50 at 3nM and 5nM, respectively

Novel potent JAK1/2/3 inhibitor

Novel Selective JAK3 Inhibitor with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Novel Selective JAK3 Inhibitor with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket