93-O17S|Ionizable Lipid for LNP

Cas No.:	2227008-67-3
Chemical Name:	93-O17S
Synonyms:	93O17S， 93 O17S
SMILES:	O=C(CCN(CCC(OCCSCCCCCCCCCCCCCC)=O)CCCN1C=NC=C1)OCCSCCCCCCCCCCCCCC
Formula:	C₄₄H₈₃N₃O₄S₂
M.Wt:	782.3
Purity:	>95%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	1. Li, Y., Yang, T., Yu, Y., et al. Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins. Biomaterials 178, 652-662 (2018). 2. Chen, J., Qiu, M., Ye, Z., et al. In situ cancer vaccination using lipi

Cat. No.	Product name	Field of application
DC53130	93-O17S	93-O17S is an imidazole-based synthetic lipidoid for in vivo mRNA delivery. Lipid nanoparticles (LNPs) with 93-O17S promotes both the cross-presentation of tumor antigens and the intracellular delivery of cGAMP (STING agonist).
DC60495	9322-O16B	9322-O16B is a lipidoid for the efficient delivery of antiCD19 mRNA CAR to murine primary macrophages. LNP 9322-O16B is more efficient than delivery with lipofectamine 2000 (LPF2K) or MC3.
DC80065	113-O12B	113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B LNP, an LN-targeting LNP delivery system, is developed for a mRNA cancer vaccine. The 113-O12B/mRNA shows enhanced expression in APCs compared with ALC-0315/mRNA, indicating the LN-specific targeting ability.