Tetraethylene glycolcas 77544-60-6|DC Chemicals

Cas No.:	77544-60-6
Chemical Name:	2-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate
Synonyms:	2-(2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate;2-[2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHOXY]-1-(P-TOLUENESULFONYL)-ETHANOL;Ethanol,2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate);[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethyl-4-methylbenzenesulfonate;tetraethyleneglycol monotosylate;tetraglycol-Ts;toluene-4-sulfonic acid 2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethyl ester;Ts-tetraglycol;Tetraethylene glycol p-toluenesulfonate
SMILES:	CC1C=CC(S(OCCOCCOCCOCCO)(=O)=O)=CC=1
Formula:	C₁₅H₂₄O₇S
M.Wt:	348.411864280701
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target:	Cleavable
In Vitro:	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References:	[1]. Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16(7):763-72.

Cat. No.	Product name	Field of application
DC39235	Fmoc-Val-Ala-PAB-OH	Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC46131	Acid-C3-SSPy	Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4, a drug-linker conjugate for ADC.
DC44707	DBCO-S-S-acid	DBCO-S-S-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC43960	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC42440	Fmoc-Gly-Gly-Phe-OH	Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC41151	Boc-Dap-NE	Boc-Dap-NE, a dipeptide, is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC41150	Fmoc-3VVD-OH	Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC41143	MC-Gly-Gly-Phe-Gly	MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
DC40833	MC-VC-PAB-Azide	MC-VC-PAB-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
DC40831	Fmoc-Val-Ala-PAB-PNP	Fmoc-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Tetraethylene glycol monotosylate