Thalidomide-piperazine hydrochloride|CAS 2228029-82-9|DC Chemicals

Cas No.:	2228029-82-9
Chemical Name:	Thalidomide-piperazine hydrochloride
Synonyms:	2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;Thalidomide-piperazine hydrochloride;Thalidomide-piperazine (hydrochloride);EN300-28311866;Z5094966714;MS-26188;AT22691;2-(2,6-dioxopiperidin-3-yl)-5-piperazin-1-ylisoindole-1,3-dione;hydrochloride;DS-022388;2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)isoindole-1,3-dione hydrochloride;2-(2,6-DIOXOPIPERIDIN-3-YL)-5-(PIPERAZIN-1-YL)ISOINDOLINE-1,3-DIONE HCL;SCHEMBL20211864;Thalidomide-5'-piperazine HCl;2228029-82-9;2-(2,6-dioxo-3-piperidyl)-5-piperazin-1-yl-isoindoline-1,3-dione;hydrochloride;HY-132971;CS-0310777;2-(2,6-Dioxopiperidin-3-yl)-5-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride
SMILES:	O=C1C2=CC(N3CCNCC3)=CC=C2C(=O)N1C1CCC(=O)NC1=O.Cl
Formula:	C₁₇H₁₉ClN₄O₄
M.Wt:	378.81
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC60559	PT-179	PT-179 is a novel orthogonal immunomodulatory drug (IMiD) derivative that selectively binds to CRBN without inducing degradation of off-target proteins. It demonstrates potent activity in degrading proteins fused to SD40, regardless of whether the fusion occurs at the N or C terminus.
DC70978	Thalidomide-piperazine hydrochloride	Thalidomide-piperazine hydrochloride represents a chemically modified derivative of the prototypic immunomodulatory drug, featuring a piperazine moiety that enhances solubility while preserving the compound's unique biological properties.
DC11588	CC-885	CC-885 (CC 885, CC885) is a novel modulator of the E3 ligase cereblon (CRBN) that exhibits strong anti-tumor activity by promoting the degradation of the protein GSPT1.