RBPJ Inhibitor-1|CAS 0|DC Chemicals

Cas No.:
Chemical Name:	RBPJ Inhibitor-1
SMILES:	O=C(N)C1=CC=C(C2=CC=NN2C)C=C1OC3=CC=CC=C3F
Formula:	C₁₇H₁₄FN₃O₂
M.Wt:	311.31
Sotrage:	Powder-20°C3 yearsIn solvent-80°C6 months-20°C1 month

Cat. No.	Product name	Field of application
DC46594	SAHM1 TFA	SAHM1 TFA is a Notch pathway inhibitor. SAHM1 TFA stabilizes hydrocarbon-stapled alpha helical peptide. SAHM1 TFA targets the protein-protein interface and prevents Notch complex assembly.
DC46314	Notch 1 TFA	Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types.
DC41036	RBPJ Inhibitor-1	RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation.
DC11930	EDD3	A novel Notch inhibitor that reduces protein expression of NOTCH1, NICD and HES1 in HEK293 cells and downregulates Notch target genes.
DC11489	6-alkynyl Fucose	A fucose analog that inhibits Dll-induced Notch signaling by reducing Notch ligand Dll1-Notch1 binding, but not Jag1.