SSD114|CAS 2319790-02-6|GABAB positive allosteric modulator

Cas No.:	2319790-02-6
Chemical Name:	SSD114 hydrochloride
Synonyms:	SSD-114,SSD 114
SMILES:	FC(F)(F)C1C=CC(C2N=C(NC3CCCCC3)N=C(OC)C=2)=CC=1.[H]Cl
Formula:	C₁₈H₂₁ClF₃N₃O
M.Wt:	387.83
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

SSD114 is a novel GABAB positive allosteric modulator. SSD114 potentiates the GABA inhibition of adenylyl-cyclase mediated by GABAB receptors. SSD114 is also effective in vivo potentiating baclofen-induced sedation/hypnosis in mice, with no effect when tested alone. These findings indicate that SSD114, a molecule with a different chemical structure compared to known GABAB PAMs, is a novel GABAB PAM with potential usefulness in the GABAB-receptor research field.

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SSD114 hydrochloride