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Cat. No. Product Name Field of Application Chemical Structure
DC65676 Fenretinide Glucuronide Monosodium Salt Featured
Fenretinide Glucuronide Monosodium Salt, is the metabolite of Fenretinide (F250000), which is a synthetic retinoid deriverative, substances related to vitamin A. They are also shown to be used for the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, and psoriasis.
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DC70246 BFL-1 inhibitor 4E14 Featured
BFL-1 inhibitor 4E14 (4E14) is a potent, selective, covalent BFL-1 inhibitor that disrupt BH3-binding activity with IC50 of 1.3 uM, targets a unique C55 residue in the BFL-1 groove.4E14 blocks BFL-1 suppression of BAX-mediated mitochondrial apoptosis.
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DC11818 SCB-4380 Featured
SCB-4380 (SCB 4380, SCB4380) is the first potent, selective inhibitor for PTPRZ (protein tyrosine phosphatase receptor-type Z) with IC50 of 0.4 uM against human Z-ICR-catalyzed hydrolysis. SCB-4380 also strongly inhibits PTPRG (IC50=0.4 uM), and shows little inhibition on PTPRA, PTPRM, PTPRS, PTPRB, PTPN1 and PTPN6. SCB-4380 inhibites PTPRZ activity in C6 glioblastoma cells, and suppresse cell migration and proliferation in vitro and tumor growth in a rat allograft model.
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DC7709 ATN-161 Featured
ATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.
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DC65677 Lumigen APS-5 Featured
Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP).
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DC23876 GSA-10 Featured
GSA-10 is a novel small-molecule positive modulator of Smoothened with EC50 of 1.2 uM in the differentiation assay.
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DC65675 4-Methylindoline Featured
DC33707 Valinomycin Featured
Valinomycin is an cyclododecadepsipeptide ionophore antibiotic that acts as an insecticide and nematocide.
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DC22403 Casopitant mesylate Featured
Casopitant (GW679769) is a potent, centrally-acting neurokinin 1 (NK1) receptor antagonist (pKi=9.48) with antidepressant and antiemetic activities.
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DC4132 CP-547632 Featured
CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively).
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DC32961 PHA-543613 Featured
PHA-543613 acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.
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DC65673 PAD-IN-2 Featured
PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis.
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DC65672 FASN-IN-5 Featured
FASN-IN-5 (example 11), a FASN inhibitor, can be used for the research of TH17- or CSF1 -mediated disease or disorder such as cancer, immunological disorders, and obesity.
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DC9325 Cilazapril (monohydrate) Featured
Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
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DC65671 PROTAC BRAF-V600E degrader-1 Featured
PROTAC BRAF-V600E degrader-1 is a potent PROTAC BRAF-V600E degrader with Kd value of 2.4 nM and 2 nM for BRAF and BRAF-V600E, respectively. PROTAC BRAF-V600E degrader-1 degrades BRAF-V600E via the ubiquitin-proteasome system (UPS). PROTAC BRAF-V600E degrader-1 can inhibit melanoma cell growth.
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DC7580 Naxagolide Featured
For the detailed information of Naxagolide, the solubility of Naxagolide in water, the solubility of Naxagolide in DMSO, the solubility of Naxagolide in PBS buffer, the animal experiment (test) of Naxagolide, the cell expriment (test) of Naxagolide, the in vivo, in vitro and clinical trial test of Naxagolide, the EC50, IC50,and Affinity of Naxagolide, Please contact DC Chemicals..
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DC45710 Pomalidomide-amino-PEG5-NH2 hydrochloride Featured
Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
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DC45712 Pomalidomide-amino-PEG3-NH2 hydrochloride Featured
Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
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DC65669 TB500 Featured
TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation.
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DC65221 BAY-6096 Featured
BAY6096, a potent, selective, and highly water-soluble α2B antagonist with IC50 = 14 nM.
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DC65665 Palmitoyl Tripeptide-8 Featured
Palmitoyl tripeptide-8 s a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient.
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DC65662 L-carnosine Featured
L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging.
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DC65661 Acetyl hexapeptide 38 Featured
Acetyl hexapeptide-38 is a bioactive peptide with upregulate adipogenesis effect and has been reported used as a cosmetic ingredient.
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DC65659 Acetyl tetrapeptide-9 Featured
Caprooyl-tetrapeptide-9 (AcTP1) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.
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DC33607 Myristoyl Pentapeptide-17 Featured
Myristoyl Pentapeptide-17 is small peptide. Myristoyl Pentapeptide-17 promotes the delivery of key ingredients for quicker lash growth, thus stimulates the hair growth at the follicle. Myristoyl Pentapeptide-17 effectively promotes the growth of eyelashes. It lengthens and thickens the eyelashes, fortifies the hair and noticeably intensifies eye expression.
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DC65656 Acetyl tetrapeptide-3 Featured
Acetyl tetrapeptide-3 is a bioactive chemical.
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DC65654 Hexapeptide-10 Featured
Hexapeptide-10 is an amino acid derivative.
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DC65653 Palmitoyl tetrapeptide-7 Featured
Palmitoyl Tetrapeptide-3 (Rigin) is a synthetic peptide, corrspending to 341-344 amino acid sequenceof IgG human H-chain, with phagocytosis stimulating activity.
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DC32408 Ac-beta-ala-his-ser-his-oh Featured
Eyeseryl, also known as Acetyl Tetrapeptide-5, humectant or hydroscopic moisturizer which helps reduce eye puffiness, improve skin elasticity as well as overall smoothness.
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DC65651 Dipeptide-2 Featured
Dipeptide 2 (N-Valyltryptophan; Val-Trp) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient.
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