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Cat. No. Product Name Field of Application Chemical Structure
DC34925 Azido-PEG23 amine Featured
Azido-PEG23 amine is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC9586 Telatinib Featured
Telatinib(Bay 57-9352) is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRα with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively.
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DC8370 Teneligliptin hydrobromide Featured
Teneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM.
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DC1065 Tenovin-1 Featured
Tenovin-1 is a p53 activator and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2.
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DC7315 Tenovin-6 Featured
Tenovin-6 is the water soluble analog of Tenovin-1 and acts as a potent SIRT1 (IC50=21 uM) and SIRT2 (IC50= 10 uM) inhibitor as well as p53 activator.
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DC9609 Terutroban Featured
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
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DC9866 Tetrabenazine Featured
Tetrabenazine has been used for dopamine uptake assays in mouse brain cells1.
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DC8054 Cariprazine (RGH-188) Featured
Cariprazine (RGH-188) is a novel putative antipsychotic drug that exerts partial agonism at dopamine D2/D3 receptors, with preferential binding to D3 receptors, and partial agonism at serotonin 5-HT1A receptors.
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DC7645 TH-237A Featured
TH-237A(meso-GS 164) is a novel neuroprotective agent exhibiting favorable permeation across the blood brain barrier.
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DC12487 TH-34 Featured
TH34 is a potent HDAC6/8/10 inhibitor, induceing DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
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DC26125 Cereblon Ligand-Linker Conjugates 3 (TFA) Featured
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
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DC11263 COX-1 Inhibitor IV(TFAP) Featured
The COX-1 Inhibitor IV, TFAP controls the biological activity of COX-1.
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DC10044 ONO4059 analog Featured
The product is the analog of ONO-4059, ONO-4059 is a highly potent and selective Btk inhibitor with an IC50 in the sub-nM range.
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DC7401 Des(benzylpyridyl) Atazanavir Featured
The N-dealkylated metabolite (M1) of Atazanavir (A790051), a HIV protease inhibitor.
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DC10469 ST-271 Featured
The tyrosine kinase inhibitor ST271 inhibited phospholipase D (PLD) activity in human neutrophils stimulated by fMet-Leu-Phe, platelet-activating factor and leukotriene B4.
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DC11272 AG-126 Featured
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
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DC10076 Thiomyristoyl Featured
Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM.
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DC7678 R-P7C3-Ome Featured
This compound is a methoxy derivative of parent compound P7C3.
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DC11384 Thymogen(Oglufanide) Featured
Thymogen(Oglufanide) is a new immunomodulating drug.
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DC8045 Tie-2 inhibitor 7 Featured
Tie inhibitor 7 is an agent that inhibits endothelial cell tube formation
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DC23013 Timosaponin A-III Featured
Timosaponin AIII (TAIII) is a steroidal saponin isolated from A. asphodeloides that has anticancer, anti-inflammatory, and antithrombotic activities and also improves learning and memory deficits in mice.
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DC23015 Timosaponin BII Featured
Timosaponin BII is an antioxidant and an anti-inflammatory agent.
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DC10478 Tinostamustine(EDO-S101) Featured
Tinostamustine is the first representative of the A-DAC principle, a new approach in chemotherapy that uses fusion technology to combine an alkylating agent with a pan-histone deacetylase inhibitor (HDAC) to simultaneously damage DNA and block damage repa
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DC8758 Tipiracil hydrochloride Featured
Tipiralacil(TPI) is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials.
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DC7327 Tirofiban(L700462;MK383) Featured
Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.
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DC2080 TMS Featured
TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM.
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DC20264 Toloxatone (MD 69276) Featured
Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor. Antidepressant.
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DC10720 Tomatidine hydrochloride Featured
Tomatidine hydrochloride is a steriodal alkaloid structurally sumilar to cyclopamine (sc-200929) but does not inhibit hedgehog pathway. It can be employed as a negative control for cyclopamine (sc-200929) and KAAD-cyclopamine.
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DC7519 Torcetrapib Featured
Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.
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DC8223 TP-0903 Featured
TP-0903 is a a high-affinity Axl inhibitor with IC50 of 27 nM.
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