Novel inducer of apoptotic cell death in TNBC cell lines without causing cytotoxicity in the normal mammary epithelial cell line

Novel inducer of apoptotic cell death in TNBC cell lines without causing cytotoxicity in the normal mammary epithelial cell line

Novel selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding

Parasympathomimetic with longer duration of action

Antibiotic, specifically inhibiting the initiation of RNA synthesis, binding isohelically to the minor groove of B-DNA at A/T rich sites

Inhibitor of ATPase activity of HSP70

Novel negative allosteric modulator of the mGlu5 receptor

Novel activator of the bone marker alkaline phosphatase (ALP), markedly promoting osteoblast differentiation, including expression of Runx2, Osterix, and Osteocalcin, mediating osteogenesis through activation of p38-β

Potent antagonist of GABA A receptors that contain alpha1 and beta2 subunits

Natural full D1 dopamine receptor agonist

Long-lasting prodrug of nalbuphine, acting as a moderate-efficacy partial agonist or antagonist of the μ-opioid receptor and as a high-efficacy partial agonist of the κ-opioid receptor

Inhibitor of Topoisomerase>DNA topoisomerase II; very potent cytotoxic antitumor agent

Anti-infective agent against certain protozoa such as Babesia, Trypanosoma, Cytauxzoon, and certain bacteria including Brucella and Streptococcus

Novel analog of etomidate, potently inhibiting 11-beta-hydroxylase without GABAA receptor positive modulatory and sedative-hypnotic activities

Serotonin antagonist and histamine antagonist

Novel inhibitor of AMA1-RON2 interaction, blocking merozoite invasion from schizont-infected RBCs; Antidepressant; Acetylcholinesterase inhibitor

Building Block

Building Block

Vasodilator for the treatment of cardiopathy and renal disorders, acting as an adenosine reuptake inhibitor.

Novel lipid-based, high-density, environmentally sensitive (HIDE) probe

Novel lipid-based, high-density, environmentally sensitive (HIDE) probe

Unique antimigration and antiangiogenic agent

Closely related co-metabolite of cyclosporin A

Competitive nicotinic receptor antagonist

D1-like full agonist with similar affinity for D1 and D5, and roughly 10-fold selectivity over D2-like receptors

Novel dose-dependent inhibitor of the SARS-CoV-2 Mac1 Macrodomain

Corticosteroid Hormone Receptor Agonist

Agonist of the androgen receptor (AR); #333333; font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans:

Antiemetic agent used in the treatment of vomiting and vertigo

Muscle relaxant, causing general central nervous system depression, relieving pain caused by strains, sprains, and other musculoskeletal conditions