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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC22207 | AP1903 Featured |
AP1903 (Rimiducid, AP-1903) is a potent, specific synthetic ligand of FKBP Phe36Val mutant (F36V-FKBP) with binding IC50 of 1.8 nM.
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| DC67803 | Thalidomide-NH-C10-COOH Featured |
Thalidomide-NH-C10-COOH (compound 6b) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology.
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| DC50065 | (S,R,S)-AHPC-CO-CI-Br Featured |
(S,R,S)-AHPC-CO-CI-Br is a novel protac building block,
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| DC67802 | Pomalidomide-PEG4-C2-NH2 hydrochloride Featured |
Pomalidomide-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in the synthesis of PROTACs.
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| DC11569 | E3 Ligand-Linker Conjugate 4 Featured |
E3 Ligand-Linker Conjugate 4 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTAC, such as MDM2 PROTAC degrader.
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| DC36456 | DMPAC-Chol Featured |
DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection. Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA.
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| DC67801 | 6-amino-N-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)hexanamide Featured |
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| DC67800 | 5-[(4-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Featured |
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| DC67799 | Thalidomide-5-NH-PEG1-NH2 hydrochloride Featured |
Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide (HY-14658)-based cereblon ligand that recruits CRBN proteins.
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| DC67798 | 5-[(6-aminobutyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione, Featured |
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| DC34571 | TL12-186 |
TL12-186 is a multikinase degrading PROTAC.
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| DC67797 | 5-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Featured |
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| DC67796 | 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-triMethyl-, (6R)- Featured |
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| DC26169 | MS1943 Featured |
MS1943 is a first-in-class, orally bioavailable EZH2 selective degrader, with an IC50 of 120 nM. MS1943 significantly reduces EZH2 protein levels in numerous triple-negative breast cancer (TNBC) and other cancer and noncancerous cell lines.
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| DC67795 | INDEX NAME NOT YET ASSIGNED Featured |
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| DC67794 | Thalidomide-O-PEG4-NHS ester Featured |
Thalidomide-O-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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| DC67793 | Thalidomide-O-amido-C6-NH2 hydrochloride Featured |
Thalidomide-O-amido-C6-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
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| DC45727 | Thalidomide-O-C5-NH2 hydrochloride Featured |
Thalidomide-O-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
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| DC8261 | (-)-JQ-1 Featured |
The (-)-JQ1 stereoisomer has no appreciable affinity to BET bromodomains,it is the negative control of +JQ-1.
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| DC5019 | (+)-JQ1 Featured |
(+)-JQ1 is a BET bromodomain inhibitor, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.
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| DC67792 | Benzonitrile, 4-(4-methyl-5-thiazolyl)-2-(phenylmethoxy)- Featured |
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| DC67791 | 5-(Benzyloxy)pyridine-2-carboxylic Acid Featured |
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| DC67790 | Benzoic acid, 4-chloro-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)- Featured |
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| DC67787 | 4-BROMO PHTHALIC ANHYDRUS Featured |
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| DC67786 | Benzoic acid, 2-(6-azaspiro[2.5]oct-6-yl)-4-iodo- Featured |
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| DC67784 | N-Boc-O-tosyl hydroxylamine Featured |
N-Boc-O-tosyl hydroxylamine is used as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines.
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| DC67783 | CRBN ligand-225 Featured |
CRBN ligand-225 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein.
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| DC67782 | Biotin NHS Featured |
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides.
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| DC67781 | CRBN ligand-224 Featured |
CRBN ligand-224 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-224 can be linked to a target protein ligand via a linker to form a PROTAC.
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| DC67780 | Thalidomide acid Featured |
Thalidomide acid is a Thalidomide analog that can be useful in PROTAC research.
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