Eed226-cooh|cas 2467965-71-3|DC Chemicals

Cas No.:	2467965-71-3
Chemical Name:	Eed226-cooh
Synonyms:	Benzoic acid, 4-[5-[(2-furanylmethyl)amino]-1,2,4-triazolo[4,3-c]pyrimidin-8-yl]-;EED226-COOH;D87223;4-[5-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-c]pyrimidin-8-yl]benzoic acid;Eed226cooh;Eed226 cooh
SMILES:	O1C([H])=C([H])C([H])=C1C([H])([H])N([H])C1=NC([H])=C(C2C([H])=C([H])C(C(=O)O[H])=C([H])C=2[H])C2=NN=C([H])N21
Formula:	C₁₇H₁₃N₅O₃
M.Wt:	335.3168
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
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DC60277	Eed226-cooh	EED226-COOH is an EED226-derived ligand for target protein EED ligand for PROTAC, binds to a ligand for VHL via linker to form UNC6852 (HY-130708) to degrade PRC2.
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DC39709	Lenalidomide-Br	Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs.
DC79845	SK2188	SK2188 is a highly efficient and selective PROTAC degrader targeting AURKA (DC50 = 3.9 nM). SK2188 induces DNA damage and cell apoptosis. SK2188 indirectly degrades MYCN, inhibits tumor cell proliferation, and provides insights into the study of MYCN-amplified neuroblastoma.
DC79178	Thalidomide-O-PEG3-COOH	Thalidomide-O-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
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DC74496	HJM-561	HJM-561 is a potent, selective and orally bioavailable EGFR PROTAC degrader, selectively degrades the EGFR C797S-containing triple mutants Del19/T790M/C797S and L858R/T790M/C797S with DC50 values of 9.2 nM and 5.8 nM, respectively.