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VH032-C7-COOH

  Cat. No.:  DC67735   Featured
Chemical Structure
2172819-77-9
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More than 5000 active chemicals with high quality for research!
Field of application
VH032-C7-COOH is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH032-C7-COOH contains an E3 ligase ligand and an alkyl linker with a terminal amine for conjugation of target protein ligands.
Cas No.: 2172819-77-9
Chemical Name: VH032-C7-COOH
Synonyms: L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;VH 032 amide-alkylC8-acid;10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecanoic acid;A1-49697;VH032-C7-COOH;2172819-77-9;CS-0119151;BP-28095;SCHEMBL19786401;E83711;10-[[(2S)-1-[(2S,4R)-4-Hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-10-oxodecanoic acid;HY-136005;AKOS040755163;(S, R, S)-AHPC-nanoly-acid;(S, R, S)-AHPC-oly-acid;(S,R,S)-AHPC-CO-C8-ACID;VH032 C7 COOH
SMILES: C(NCC1=CC=C(C2SC=NC=2C)C=C1)(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCC(O)=O
Formula: C32H46N4O6S
M.Wt: 614.795847415924
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC67762 CRBN ligand-204 CRBN ligand-204 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-204 can be linked to a target protein ligand via a linker to form a PROTAC.
DC67752 5-Amino-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]pentanamide
DC67751 tert-butyl 3-({3-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]prop-2-yn-1-yl}oxy)propanoate
DC67750 Desamino lenalidomide-5-acetonitrile Desamino lenalidomide-5-acetonitrile is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-acetonitrile can be linked to a target protein ligand via a linker to form a PROTAC.
DC67749 Pomalidomide-C2-acid Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
DC67748 Pomalidomide 4'-alkylC3-acid Pomalidomide 4'-alkylC3-acid is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs.
DC67747 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-4-(2-propyn-1-yloxy)-2H-isoindol-2-yl]-
DC67746 E3 ligase Ligand 63 E3 ligase Ligand 63 is an E3 ligase ligand that can be used to synthesize CDK2 degrader 2 (HY-163815).
DC67745 (S,R,S)-AHPC--CO-PEG1-C2-amine HCl
DC67744 Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
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