tri-GalNAc-PEG3-Azide|CAS 2925590-71-0|DC Chemicals

Cas No.:	2925590-71-0
Chemical Name:	tri-GalNAc-PEG3-Azide
Synonyms:	AT42652;TRI-GALNAC-PEG3-AZIDE;2925590-71-0
SMILES:	O1[C@H]([C@@H]([C@H]([C@H]([C@H]1CO)O)O)NC(C)=O)OCCCCC(NCCCNC(CCOCC(COCCC(NCCCNC(CCCCO[C@H]1[C@H]([C@H]([C@H]([C@@H](CO)O1)O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)NC(C)=O)=O)=O)NC(CCOCCOCCOCCN=[N+]=[N-])=O)=O)=O
Formula:	C₇₀H₁₂₅N₁₃O₃₁
M.Wt:	1644.83
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68086	tri-GalNAc biotin	tri-GalNAc biotin is a biotinylated ASGPR (Asialoglycoprotein receptor) ligand. tri-GalNAc biotin promotes cellular uptake of neutravidin (NA) via ASGPR. tri-GalNAc biotin delivers neutravidin to lysosomes for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC).
DC68015	tri-GalNAc-PEG3-Azide	tri-GalNAc-PEG3-Azide is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; each molecule incorporates three ASGPR ligands with a PEG3 linker and azide group reactive handle ready for conjugation. Upon binding to the ASGPR, tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to hepatocytes. Can be used to generate LYTACs, or labeled with dye for tissue imaging.
DC68014	Tri-GalNAc Acid	Triantennary GalNAc Acid is an asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development.
DC68010	Tri-GalNAc-PEG4-DBCO	Tri-GalNAc-biotin is an asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development, comprising a triantennary N-acetylgalactosamine (GalNAc) joined by a PEG linker to DBCO.
DC68008	Tris-GalNAc-β-Ala-PEG3-FITC	The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007	Tris-GalNAc-β-Ala-PEG3-MAL	A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006	Tri-GalNAc-PEG2000-DSPE	Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005	Tris-GalNAc-PEG5-sulfo-NHS Ester	An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004	Tris-GalNAc-β-Ala-PEG3-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003	Tris-GalNAc-β-Ala-PEG4-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry