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Desamino lenalidomide-5-acetonitrile

  Cat. No.:  DC67750   Featured
Chemical Structure
1010100-27-2
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More than 5000 active chemicals with high quality for research!
Field of application
Desamino lenalidomide-5-acetonitrile is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-acetonitrile can be linked to a target protein ligand via a linker to form a PROTAC.
Cas No.: 1010100-27-2
Chemical Name: 2-(2,6-Dioxo-piperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindole-5-carbonitrile
Synonyms: 2-(2,6-Dioxo-piperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindole-5-carbonitrile;1H-Isoindole-5-carbonitrile, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-;2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindoline-5-carbonitrile;CS-0369481;2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindole-5-carbonitrile;1010100-27-2;A1-09757;AKOS037654835;DB-180957;1-Oxo-2-(2,6-dioxopiperidin-3-yl)isoindoline-5-carbonitrile;AT32858;2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindoline-5-carbonitrile;Z2945048005;TQR1046;MS-20845;NYVGCNSACSJVJQ-UHFFFAOYSA-N;SCHEMBL1413817
SMILES: C1(=O)C2=C(C=C(C#N)C=C2)CN1C1CCC(=O)NC1=O
Formula: C14H11N3O3
M.Wt: 269.255442857742
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC67762 CRBN ligand-204 CRBN ligand-204 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-204 can be linked to a target protein ligand via a linker to form a PROTAC.
DC67752 5-Amino-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]pentanamide
DC67751 tert-butyl 3-({3-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]prop-2-yn-1-yl}oxy)propanoate
DC67750 Desamino lenalidomide-5-acetonitrile Desamino lenalidomide-5-acetonitrile is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-acetonitrile can be linked to a target protein ligand via a linker to form a PROTAC.
DC67749 Pomalidomide-C2-acid Pomalidomide-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
DC67748 Pomalidomide 4'-alkylC3-acid Pomalidomide 4'-alkylC3-acid is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs.
DC67747 2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-4-(2-propyn-1-yloxy)-2H-isoindol-2-yl]-
DC67746 E3 ligase Ligand 63 E3 ligase Ligand 63 is an E3 ligase ligand that can be used to synthesize CDK2 degrader 2 (HY-163815).
DC67745 (S,R,S)-AHPC--CO-PEG1-C2-amine HCl
DC67744 Thalidomide-O-amido-C4-NH2 hydrochloride Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs.
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