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Pomalidomide-PEG1-azide

  Cat. No.:  DC67757   Featured
Chemical Structure
2133360-04-8
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More than 5000 active chemicals with high quality for research!
Field of application
Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131). Pomalidomide-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cas No.: 2133360-04-8
Chemical Name: Pomalidomide-PEG1-azide
Synonyms: Pomalidomide-PEG1-azide;2-(2-Azidoethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide;Crosslinker−E3 ligase ligand conjugate;Partial PROTAC;Template for synthesis of targeted protein degrader;Pomalidomide-NH-PEG1-azide;SCHEMBL23037446;2-(2-azidoethoxy)-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]acetamide;2133360-04-8;CS-0112205;DA-66818;2-(2-azidoethoxy)-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]acetamide;Pomalidomide-NH-PEG1-N3;MS-26789;SY325568;HY-133138;E85792;AKOS040743782;2-(2-Azidoethoxy)-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]acetamide;Pomalidomide-NH-CO-PEG1-N3;MFCD32198602
SMILES: O=C1C(CCC(N1)=O)N1C(C2C=CC=C(C=2C1=O)NC(COCCN=[N+]=[N-])=O)=O
Formula: C17H16N6O6
M.Wt: 400.35
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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