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CRBN ligand-878

  Cat. No.:  DC67828   Featured
Chemical Structure
1997302-16-5
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More than 5000 active chemicals with high quality for research!
Field of application
CRBN ligand-878 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-878 can be linked to a target protein ligand via a linker to form a PROTAC.
Cas No.: 1997302-16-5
Chemical Name: tert-butyl ((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
Synonyms: tert-butyl ((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate;ert-Butyl ((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate;tert-butyl N-[(2S)-1-[(2S,4R)-4-hydroxy-2-{[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl}pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate;tert-Butyl((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate;tert-butyl N-[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate;SCHEMBL21458662;C28H40N4O5S;CS-0021799;G72700;1997302-16-5
SMILES: C(N[C@H](C1=CC=C(C2SC=NC=2C)C=C1)C)(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O
Formula: C28H40N4O5S
M.Wt: 544.71
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC67845 N-Me-Thalidomide 4-fluoride N-Me-Thalidomide 4-fluoride is a ligand for E3 ligase, used for the synthesis of Anti-inflammatory agent 70 .
DC67844 CRBN ligand-880 CRBN ligand-880 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-880 can be linked to a target protein ligand via a linker to form a PROTAC.
DC67843 6-hydroxy-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
DC67842 Tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperazine-1-carboxylate
DC67841 Boc-NH-PEG4 Boc-NH-PEG4 (PROTAC Linker 12) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
DC67840 tert-Butyl (6-hydroxyhexyl)carbamate tert-Butyl (6-hydroxyhexyl)carbamate is a PROTAC linker that can be used in the synthesis of PROTACs.
DC67839 tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate (Standard) tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate (Standard) is the analytical standard of tert-Butyl N-(2,6-dioxopiperidin-3-yl)carbamate. This product is intended for research and analytical applications.
DC67838 3-amino-1-methylpiperidine-2,6-dione hydrochloride
DC67837 (S)-3-Amino-piperidine-2,6-dione hydrochloride
DC67836 (R)-3-Aminopyrrolidine-2,5-dione (R)-3-Aminopyrrolidine-2,5-dione is a potential anticonvulsant agent and its derivatives have comparable in vivo efficacy.
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