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I-BET762 carboxylic acid

  Cat. No.:  DC67833   Featured
Chemical Structure
1300019-38-8
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Field of application
I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1.
Cas No.: 1300019-38-8
Chemical Name: I-BET762 carboxylic acid
Synonyms: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2;I-BET762 carboxylic acid;Target Protein-binding moiety 4;PROTAC BRD4-binding moiety 2;GSK525762A carboxylic acid;Molibresib carboxylic acid;4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine-4-acetic acid, 6-(4-chlorophenyl)-8-methoxy-1-methyl-, (4S)-;CS-0028499;[(4S)-6-(4-Chlorophenyl)-1-methyl-8-(methyloxy)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]acetic acid;EX-A3917;2-((4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)acetic acid;2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]acetic acid;G16204;BDBM50441160;(S)-2-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)acetic acid;SCHEMBL1820357;DA-78201;HY-107443;CHEMBL2430881;AKOS037653346;VEIZLTSJCDOIBH-INIZCTEOSA-N;1300019-38-8
SMILES: N12C(C)=NN=C1[C@H](CC(O)=O)N=C(C1=CC=C(Cl)C=C1)C1=CC(OC)=CC=C12
Formula: C20H17ClN4O3
M.Wt: 396.83
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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