cft1946 |CAS 2882165-79-7|DC Chemicals

Cas No.:	2882165-79-7
Chemical Name:	(3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decane
SMILES:	CN1C(C(C(N(CCC2=O)C(N2)=O)=N1)=C3)=CC(N(CC4)CCC4(O)CC(N5CCC6(C[C@@H](N(C=NC7=CC=C8OC(C(F)=CC=C9N[S](N(C)CC)(=O)=O)=C9C#N)C(C7=C8)=O)CO6)CC5)=O)=C3F
Formula:	C₄₅H₄₉F₂N₁₁O₉S
M.Wt:	958.01
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68008	Tris-GalNAc-β-Ala-PEG3-FITC	The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007	Tris-GalNAc-β-Ala-PEG3-MAL	A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006	Tri-GalNAc-PEG2000-DSPE	Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005	Tris-GalNAc-PEG5-sulfo-NHS Ester	An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004	Tris-GalNAc-β-Ala-PEG3-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003	Tris-GalNAc-β-Ala-PEG4-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002	Tris-β-GalNAc-β-Ala-PEG3-N3	(β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001	Tris-β-GalNAc-PEG3-Azide	Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000	Tris-GalNAc-β-Ala-PEG3-NH2
DC67999	Tris-GalNAc-Ahx-NH2

CFT1946