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PZ703b

  Cat. No.:  DC47361   Featured
Chemical Structure
2471970-56-4
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More than 5000 active chemicals with high quality for research!
Field of application
PZ703b is highly potent in killing BCL-XL dependent, BCL-2 dependent, and BCL-XL/BCL-2 dual-dependent cells in an E3 ligase (VHL)-dependent fashion.
Cas No.: 2471970-56-4
Chemical Name: INDEX NAME NOT YET ASSIGNED
Synonyms: PZ703b
SMILES: C(N1CCN(C2C=CC(C(=O)NS(C3C=CC(N[C@@H](CSC4C=CC=CC=4)CCN4CCOCC4)=C(S(=O)(=O)C(F)(F)F)C=3)(=O)=O)=CC=2)CC1)C1C[C@](C)(CNC(=O)CCCCCCCCC(=O)N[C@@H](C(C)(C)C)C(N2C[C@H](O)C[C@H]2C(=O)N[C@H](C2C=CC(C3=C(N=CS3)C)=CC=2)C)=O)CCC=1C1C=CC(Cl)=CC=1
Formula: C80H102ClF3N10O11S4
M.Wt: 1600.43450498581
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC68008 Tris-GalNAc-β-Ala-PEG3-FITC The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007 Tris-GalNAc-β-Ala-PEG3-MAL A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006 Tri-GalNAc-PEG2000-DSPE Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005 Tris-GalNAc-PEG5-sulfo-NHS Ester An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004 Tris-GalNAc-β-Ala-PEG3-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003 Tris-GalNAc-β-Ala-PEG4-DBCO Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002 Tris-β-GalNAc-β-Ala-PEG3-N3 (β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001 Tris-β-GalNAc-PEG3-Azide Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000 Tris-GalNAc-β-Ala-PEG3-NH2
DC67999 Tris-GalNAc-Ahx-NH2
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