The first inhibitor of forkhead Box Protein C2 (FOXC2)

Novel potent acetylcholinesterase (AChE) inhibitor

Potent and HDAC class I-selective inhibitor

Topical nonnucleoside reverse transcriptase inhibitor, partially preventing vaginal RT-SHIV infection of macaques

Novel specific inhibitor of HA-mediated viral entry, inhibiting HPAI H5N1 virus strain A/Hong Kong/H5N1

Antibacterial agent, with a relatively narrow spectrum against bacteria and a very high CC 50 value

Novel antibacterial agent, remarkably potent against antibiotic-resistant bacterial strains such as MDR A. baumannii , ESBL-producing Klebsiella pneumoniae, VRE, and MRSA

Potent antibacterial agent against a wide range of Gram-positive and Gram-negative bacteria

The first selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase

Deuterium-substituted anticancer agent, plinabulin, exhibiting better pharmacokinetic characteristics than that of plinabulin

Novel detergent, showing enhanced stability to all tested proteins compared to a gold standard detergent (DDM)

Novel detergent, showing enhanced stability to all tested proteins compared to a gold standard detergent (DDM)

Novel non-hemolytic and low toxic inhibitor of metallo-β-lactamases (MBLs), restoring the activity of meropenem against Escherichia coli, Citrobacter freundii, Proteus mirabilis and Klebsiella pneumonia, which carried resistance genes of blaNDM-1

Novel inhibitor of dengue and West Nile virus NS2B-NS3 protease

Novel Inhibitor of Mycobacterium tuberculosis α-1,4-Glucan Branching Enzyme (GlgB)

Prodrug of MB05032, acting as potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes

Novel potent inhibitor of the membrane-bound retinoid isomerase RPE65

Natural Anti-inflammation Agent, Attenuating Amyloid Plaques by Inducing Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model

Novel potent inhibitor of May1 with Ki = 12 ± 1 nM, also inhibiting wild-type HIV-1 protease with Ki = 32 ± 5 pM and three drug resistance-associated mutants with Ki values ranging from 24 to 320 pM

Novel potent tyrosinase inhibitor from the Gram-negative bacterium Massilia albidiflava DSM 17472T

Novel, active, and less toxic anti-tuberculosis (anti-TB) agent

Inhibitor of voltage-gated K(+) (Kv) channels Kv1.3 and Kv1.5

Novel highly efficient dual type I/II FMS-like tyrosine kinase inhibitor, disrupting the growth of leukemic cells

Inhibitor of neuronal norepinephrine reuptake, reducing symptoms of anxiety associated with depression.

Novel stable antibody-drug conjugate (ADC) in mouse serum

Novel selective MAO-B inhibitor

Novel potent and competitive inhibitor of MAO-B (IC 50 : 0.51 μM), also inhibiting BChE (IC 50 : 7.00 μM)

Novel potent selective and competitive inhibitor of MAO-B (IC 50 : 0.69 μM)

Potent and selective MAO-B inhibitor

Novel potent and highly selective MAO-B Inhibitor