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Abamectin

  Cat. No.:  DC36108   Featured
Chemical Structure
71751-41-2
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More than 5000 active chemicals with high quality for research!
Field of application
Abamectin is a mixture of the macrocyclic lactones Avermectin B1a and Avermectin B1b. It has both insecticidal and anthelmintic actions and is used in both agriculture and veterinary medicine. Abamectin can inhibit nicotinic acetylcholine receptors of worms and can also inhibit chikungunya and yellow fever viruses. It is sometimes used for mosquito control.
Cas No.: 71751-41-2
Chemical Name: Avermectin B1a
Synonyms: ABAMECTIN;Abamectin solution;Abamectin Standard;Mixture of Avermectin B1a and Avermectin B1b;Affirm;Agri-Mek;Avermectin;Avermectin B1;Avid;Zephyr;EPU-105;zephyr;Zephy;WAKO016-20361;SADDLE;mk936;avomec;avidec;Avermectin B1a-Avermectin B1b mixt.;mixture of avermectin b1a and avermectin b1b;MEDAMEC;DYNAMEC(R);DYNAMEC;BERMECTINE;AVM;AVID(R);avid;AVERMECTINE;AVERMECTIN B1, STREPTOMYCES AVERMITILIS;AVERMECTIN B1;AVERMECTIN B;AVERMECTIN;AGRI-MEK(R);agri-mek;affirm;ACIMIC;ABAMECTINE;ABACIDE
SMILES: C1[C@@H]([C@@H](O[C@@H]2O[C@H]([C@H](O)[C@@H](OC)C2)C)[C@H](C)O[C@H]1O[C@H]1[C@@H](C)C=CC=C2CO[C@]3([C@]2(O)[C@@]([H])(C=C([C@H]3O)C)C(=O)O[C@H]2C[C@@]([H])(CC=C1C)O[C@@]1(C=C[C@H](C)[C@@]([H])([C@H](CC)C)O1)C2)[H])OC |c:26,t:24,50|
Formula: C48H72O14
M.Wt: 873.07689666748
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. IC50 Value: N/ATarget: AntiparasiticAvermectin B1 is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b. These two components, B1a and B1b have very similar biological and toxicological properties. The avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium Streptomyces avermitilis. Avermectin B1 is a natural fermentation product of this bacterium.
References: [1]. Mogg TD, Pollitt CC, Willmore JP, Thompson H.Efficacy of avermectin B1 given orally against equine intestinal strongyles and Onchocera microfilaria.Aust Vet J. 1990 Nov;67(11):399-401. [2]. De Chaneet GC, Casey R, Dixon FF, Besier RB, Mitchell RK.Effect of avermectin B1 and benzimidazole anthelmintics on worm egg output of treated cattle.Aust Vet J. 1988 Mar;65(3):85-6. [3]. Seaman JT, Eagleson JS, Carrigan MJ, Webb RF.Avermectin B1 toxicity in a herd of Murray Grey cattle.Aust Vet J. 1987 Sep;64(9):284-5. [4]. Murty US, Jyothi KN, Jamil K.Effect of avermectin B1 (L-676) a metabolite from Streptomyces avermilitis on immatures of Culex quinquefasciatus.Indian J Med Res. 1987 May;85:539-41. [5]. Parrish MD, Roberts RB.Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae).J Econ Entomol. 1984 Jun;77(3):769-72.
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