NP161|CAS 1421763-05-4|DC Chemicals

Cas No.:	1421763-05-4
Chemical Name:	2-(cyclohexyldisulfanyl)-5-nitro-1H-benzo[d]imidazole
Synonyms:	NP 161;NP-161
SMILES:	C(SSC1CCCCC1)1=NC2=CC([N+]([O-])=O)=CC=C2N1
Formula:	C₁₃H₁₅N₃O₂S₂
M.Wt:	309.402
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

NP161 is a potent and selective inhibitor of extracellular TRX (Thioredoxin 1) in vitro with IC50 of 0.54 uM; enhances cytokine outputs of alternatively activated macrophages, significantly attenuate TG2 activity and 5-BP incorporation in both M0 and M1 macrophages.

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