Methyl 3,4-dihydroxybenzoate |CAS 2150-43-8|DC Chemicals

Cas No.:	2150-43-8
Chemical Name:	Methyl 3,4-dihydroxybenzoate
Synonyms:	Methyl 3,4-dihydroxybenzoate;3,4-Dihydroxybenzoic acid methyl ester;Methyl protocatechuate;3,4-dihydroxy methyl benzoate;3,4-dihydroxy-6-methoxycarbonylbenzene;3,4-DIHYDROXY-BENZOIC ACID METHYL ESTER;Protocatechuic Acid Methyl Ester;Protocatechuic acid, methyl ester;Benzoic acid, 3,4-dihydroxy-, methyl ester;3,4-Dihydroxymethylbenzoate;3,4-Dihydroxybenzoic acid methyl;CUFLZUDASVUNOE-UHFFFAOYSA-N;G72J90268X;MDHB;methyl-protocatechuate;methyl 3,4-dihydroxy;rarechem al bf 0069;protocatechuic acid methyl;Methyl3,4-Dihydroxyb;Protocatechuic acid methyl ester;3,4-Dihydroxybenzoic Acid Methyl Ester;Methyl Protocatechuate;NSC-146458;UNII-G72J90268X;NSC146458;methyl esterprotocatechuic acid;AKOS006230366;Benzoic acid,4-dihydroxy-, methyl ester;CCG-266347;PROTOCATECHUIC ACID METHYLESTER;SY016131;3,4-dihydroxy-benzoic acid methyl ester;CHEBI:132366;AC-11616;3,4-Dihydroxy benzoic acid methyl ester;M1943;HE9;EN300-185840;SCHEMBL38624;DTXCID70252938;s3869;CS-Z0026;HY-Z0548;InChI=1/C8H8O4/c1-12-8(11)5-2-3-6(9)7(10)4-5/h2-4,9-10H,1H3;AMY246;Z91855314;methyl 3,4-bis(oxidanyl)benzoate;BDBM50242283;Q10354668;J-522112;FT-0614327;DTXSID20301804;MFCD00016437;MDHB compound;CUFLZUDASVUNOE-UHFFFAOYSA-;TS-02273;2150-43-8;AC-34361;CHEMBL486027;protocatechuic acid, methyl ester;methyl protocatechuate;ConMedNP.2945;Dataset-S1.17;3,4-dihydroxybenzoic acid methyl ester
SMILES:	O(C([H])([H])[H])C(C1C([H])=C([H])C(=C(C=1[H])O[H])O[H])=O
Formula:	C₈H₈O₄
M.Wt:	168.1467
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

In Vitro Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) alleviates the toxic effects of F- via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells. In Vivo Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester;Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F- accumulation and oxidative stress. It prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2.

Cat. No.	Product name	Field of application
DC31074	Isopropyl myristate	Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC75868	AZ14133346	AZ14133346 (compound 36) is a potent and selective inhibitor of EGFR Exon20 insertions, with the IC50 of 85 nM. AZ14133346 plays an important role in cancer research.
DC75865	TI17	TI17 represents a novel class of targeted anticancer agents that specifically disrupt DNA damage repair mechanisms in malignant cells.
DC75816	Nisoxetine	Nisoxetine acts as a highly selective and potent noradrenaline transporter (NET) antagonist, exhibiting a binding affinity (Kd) of 0.76 nM. In addition to its antidepressant properties, nisoxetine functions as a local anesthetic by inhibiting voltage-gated sodium channels. This dual pharmacological activity makes it a compound of interest for both neurological and pain management research.
DC75641	GENZ-644282 TFA salt	Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
DC75325	PSMA-617 TFA	PSMA-617, also know as vipivotide tetraxetan, is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
DC75202	Fosaprepitant free acid	Fosaprepitant, also known as MK0517, is an antiemetic drug, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. Fosaprepitant is a weak inhibitor of CYP3A4, and aprepitant, the active moiety, is a substrate, inhibitor, and inducer of CYP3A4
DC74748	O4I4	O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
DC74684	ZH8667	ZH8667 is a trace amine-associated receptor 1 (TAAR1)–Gs agonist.
DC74646	EB-PSMA-617	EB-PSMA-617 is an Evans blue-modified prostate-specific membrane antigen (PSMA) 617 ligand for making 177Lu-EB-PSMA, which is potential useful for Metastatic Castration-Resistant Prostate Cancer.