MLS 0263839|MLS0263839|CAS 716375-92-7|DC Chemicals

Cas No.:	716375-92-7
Chemical Name:	N,N-Dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide
Synonyms:	N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide;MLS000773738;MLS003116069;KUC104125N;SMR000364449;MLS002460504;BDBM34966;cid_5040456;HMS2218K20;HMS3340G17;VU0316361-2;Q27164871;Z56798522;3-(3-keto-1,2-benzothiazol-2-yl)-N,N-dimethyl-benzenesulfonamide;N,N-dimethyl-3-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzenesulfonamide;N,N-Dimethyl-3-(
SMILES:	S(C1C=CC=C(C=1)N1C(C2C=CC=CC=2S1)=O)(N(C)C)(=O)=O
Formula:	C₁₅H₁₄N₂O₃S₂
M.Wt:	334.413260936737
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	1. Kiffer-Moreira T, et al. J Bone Miner Res. 2013 Jan;28(1):81-91. 2. Huesa C, et al. Biochem Biophys Rep. 2015 Dec 1;4:196-201.

Description:	MLS 0263839 is a potent, specific inhibitor of the phosphatase PHOSPHO1 with IC50 of 0.14 uM, shows minimal cross-inhibition of TNAP and no inhibition of ENPP1 activity; suppresses vascular smooth muscle cell calcification in cimbined with MLS 0038949.
References:	References 1. Kiffer-Moreira T, et al. J Bone Miner Res. 2013 Jan;28(1):81-91. 2. Huesa C, et al. Biochem Biophys Rep. 2015 Dec 1;4:196-201. View Related Products by Target Protein Phosphatase/PTP

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