OAT-2068 |CAS 2221950-65-6|DC Chemicals

Cas No.:	2221950-65-6
Chemical Name:	3-(4-((2S,5S)-2-(4-Chlorobenzyl)-4-isobutyl-5-methylpiperazin-1-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine
Synonyms:	1H-1,2,4-Triazol-3-amine, 5-[4-[(2S,5S)-2-[(4-chlorophenyl)methyl]-5-methyl-4-(2-methylpropyl)-1-piperazinyl]-1-piperidinyl]-;OAT-2068
SMILES:	N1C(N2CCC(N3C[C@H](C)N(CC(C)C)C[C@@H]3CC3=CC=C(Cl)C=C3)CC2)=NC(N)=N1
Formula:	C₂₃H₃₆ClN₇
M.Wt:	446.03
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

OAT-2068 is a potent, selective, orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1) with IC50 of 29 nM, 143-fold selectivity over mAMCase; exhibits excellent pharmacokinetic profile and is an ideal and unique tool for studying the role of CHIT1 in biological models.

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