Difamilast(OPA-15406)|CAS 937782-05-3|DC Chemicals

Cas No.:	937782-05-3
Chemical Name:	Difamilast
Synonyms:	Difamilast;T3U32GLJ0F;Difamilast [USAN];Difamilast (JAN/USAN);MM36;GTPL9776;BDBM389126;USRE46792, 352;DB14987;example 352 [WO2007058338];D11314;N-[2-(4-difluoromethoxy-3-isopropoxyphenyl)oxazol-4-ylmethyl]-2-ethoxybenzamide;N-((2-(4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl)-1,3-oxazol-4-yl)methyl)-2-ethoxybenzamide;N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide;Benzamide, N-((2-(4-(;N-[[2-[4-(Difluoromethoxy)-3-(1-methylethoxy)phenyl]-4-oxazolyl]methyl]-2-ethoxybenzamide (ACI);MM 36;N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide;OPA 15406
SMILES:	O=C(C1C(OCC)=CC=CC=1)NCC1=COC(C2C=C(OC(C)C)C(OC(F)F)=CC=2)=N1
Formula:	C₂₃H₂₄F₂N₂O₅
M.Wt:	446.443873405457
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM). Dermatitis Phase 2 Clinical

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