Casopitant mesylate| CAS 414910-30-8

Cas No.:	414910-30-8
Chemical Name:	Casopitant Mesylate
Synonyms:	Casopitant Mesylate;(2R,4S)-4-(4-acetylpiperazin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide,methanesulfonic acid;Casopitant
SMILES:	CN(C(N1[C@@H](C2=C(C)C=C(F)C=C2)C[C@@H](N2CCN(C(=O)C)CC2)CC1)=O)[C@@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)C.CS(=O)(=O)O
Formula:	C₃₁H₃₉F₇N₄O₅S
M.Wt:	712.718991518021
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Casopitant (GW679769) is a potent, centrally-acting neurokinin 1 (NK1) receptor antagonist (pKi=9.48) with antidepressant and antiemetic activities; demonstrates potential for treatment of chemotherapy-induced nausea and vomiting (CINV).Chemotherapeutic AgentsPhase 2 Discontinued

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