| Cas No.: | 1351056-65-9 |
| Chemical Name: | (S)-2-amino-2-(4-[(6-methylheptyl)-oxy]phenethyl)pentan-1-ol |
| Synonyms: | OSU 2S |
| Formula: | C21H37NO2 |
| M.Wt: | 335.532 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A non-immunosuppressive FTY720 analogue, PKCδ activator with higher antiproliferative potency with IC50 of 2.4, 2.4, and 3.5 uM in Huh7, Hep3B, and PLC5 cells, respectively; exhibited higher in vitro antiproliferative efficacy relative to FTY720 against HCC cells without cytotoxicity in normal hepatocytes, although devoid of S1P1 receptor activity; induces caspase-dependent apoptosis through ROS-dependent PKCδ activation in HCC tumor cells. |

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