| Cas No.: | 4338-47-0 |
| Chemical Name: | Adenosine, N-(2-furanylmethyl)- |
| Synonyms: | N6-Furfuryladenosine;FAdo |
| SMILES: | O1C=CC=C1CNC1=NC=NC2=C1N=CN2C1OC(CO)C(O)C1O |
| Formula: | C15H17N5O5 |
| M.Wt: | 347.32598 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines; inhibits MiPaCa-2 cell proliferation with IC50 of 0.27 uM; induceds marked suppression of CCND2 transcription and rapidly suppresses cyclin D1 and D2 protein expression in primary myeloma cells and tumor lines, causing cell cycle arrest, tumor cell-selective apoptosis, and inhibition of myeloma growth in xenografted mice; also can activate PINK1 in cells independent of mitochondrial depolarization. |

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