ECBN hydrochloride|cas 1029890-89-8|DC Chemicals

Cas No.:	1029890-89-8
Chemical Name:	1-(4R,5R)-4,5-Dihydroxy-L-ornithine-Echinocandin B Hydrochloride
Synonyms:	ECBN;ECBN HCL;Echinocandin B nucleus hydrochloride;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1;1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)
SMILES:	Cl[H].O[C@@H]1[C@@]2([H])C(N([H])[C@@H]([C@H](C[C@@H](C(N([H])[C@@]([H])([C@@H](C)O)C(N3C[C@@H](C[C@@]3([H])C(N([H])[C@@]([H])([C@@H]([C@H](C3C=CC(=CC=3)O)O)O)C(N([H])[C@@]([H])([C@@H](C)O)C(N2C[C@@H]1C)=O)=O)=O)O)=O)=O)N([H])[H])O)O)=O
Formula:	C₃₄H₅₂ClN₇O₁₅
M.Wt:	834.3
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	A-30912A nucleus hydrochloride is the product of the reaction catalyzed by Echinocandin B (ECB) deacylase[1].
In Vitro:	Echinocandin B (ECB), obtained by the fermentation of Aspergillus nidulans and Aspergillus rugulosus, is known as one of the natural cyclic hexapeptides that have a linoleoyl side chain, which inhibits a crucial enzyme in fungal cell wall biosynthesis, β-(1,3)-D-glucan synthase[1].
References:	[1]. Lei Shao, et al. Efficient bioconversion of echinocandin B to its nucleus by overexpression of deacylase genes in different host strains. Appl Environ Microbiol. 2013 Feb;79(4):1126-33.

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