AS-0017445|CAS |DC Chemicals

Cas No.:
Chemical Name:	AS-0017445
SMILES:	O=C(N(CC1=CN(C)N=N1)C[C@@]23C(N(C4=CN=CC5=C4C=CC=C5)C[C@@H]3CNC(C)C)=O)C6=C2C=C(Cl)C=C6
Formula:	C₂₉H₃₀ClN₇O₂
M.Wt:	544.05
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC40958	A2ti-2	A2ti-2 is a selective and low-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 230 μM. A2ti-2 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-2 prevents human papillomavirus type 16 (HPV16) infection.
DC40957	A2ti-1	A2ti-1 is a selective and high-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-1 prevents human papillomavirus type 16 (HPV16) infection.
DC76105	Secutrelvir	Secutrelvir is the inhibitor for 3CL protease that exhibits antiviral activity through inhibition of SARS-CoV-2 replication.
DC76104	Dihydro K22	Dihydro K22 is a derivative of the antiviral agent K22. Pyridoxine tri(2-hexyldecanoate) is a cosmetic ingredient.
DC76103	BP-198	BP-198 is an Mpro PROTAC degrader. BP-198 promotes the ubiquitination and degradation of Mpro. BP-198 has antiviral effects against SARS-CoV-2 (IC50: 11.8 μM) and has stronger activity against drug-resistant viruses.
DC76102	AS-0017445	AS-0017445 is an inhibitor targeting the main protease of both the current coronavirus and the virus that caused the Middle East Respiratory Syndrome (MERS) outbreak. AS-0017445 inhibits the viral protein processing in host cells and thus prevents viral replication.
DC72841	5-Bromo-2′-deoxy-2′-fluorouridine	5-Bromo-2′-deoxy-2′-fluorouridine (Example 1), a 5-halo analog, is potential as an antiviral agent.
DC72299	LabMol-301	LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death.
DC72298	NITD-688	NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV).
DC71199	Hydroxyethylamine	Hydroxyethylamine (Compd VII) is a SARS-CoV-2 3CLpro inhibitor with an IC50 of ~10 μM in the spread assay. Hydroxyethylamine has potent antiviral activities.