D-578|CAS 2454461-06-2|DC Chemicals

Cas No.:	2454461-06-2
Chemical Name:	D-578
Formula:	C₂₆H₂₅F₂N₃O₂S
M.Wt:	481.56

Cat. No.	Product name	Field of application
DC41416	13-Hydroxyisobakuchiol	Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol isolated from Psoralea corylifolia (L.), is a potent monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter (DAT) (IC50=0.58 μM) and norepinephrine transporter (NET) (IC50=0.69 μM) than for the serotonin transporter (SERT) (IC50=312.02 μM). 13-Hydroxyisobakuchiol has the potential for the research of disorders such as Parkinson's disease, depression, and cocaine addiction.
DC41234	Nisoxetine hydrochloride	Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. Nisoxetine hydrochloride is an antidepressant and local anesthetic, it can block voltage-gated sodium channels.
DC9513	Radafaxine (hydrochloride)	Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat
DC9630	Dapoxetine (hydrochloride)	Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor(SSRI).
DC76777	Cendifensine	Cendifensine is the inhibitor for monoamine reuptake that inhibits the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).
DC76776	3-Bromoamphetamine hydrochloride	3-Bromoamphetamine hydrochloride is a para-substituted amphetamine that acts as a monoamine releasing agent.
DC76775	(2S,3S,11bR)-Dihydrotetrabenazine	(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. (2S,3S,11bR)-Dihydrotetrabenazine inhibits vesicular transport of monoamine neurotransmitters like dopamine and serotonin, reducing their synaptic release. (2S,3S,11bR)-Dihydrotetrabenazine is promising for research of Huntington's chorea and other hyperkinetic disorders.
DC73646	ZINC000443438219	ZINC000443438219 (Compound 8219) is a highly potent, selective and non-competitive inhibitor of serotonin transporter (SERT) with Ki of 3 nM.
DC73645	ZINC000006658090	ZINC000006658090 (Compound 8090) is a highly potent, selective and non-competitive inhibitor of serotonin transporter (SERT) with Ki of 14 nM.
DC73644	SRI-32743	SRI-32743 is a novel allosteric modulator of dopamine transporter (DAT), attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter.