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JLT048

  Cat. No.:  DC73205  
Chemical Structure
664357-58-8
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More than 5000 active chemicals with high quality for research!
Field of application
JLT048 is a small molecule inhibitor of tyrosyl-DNA-phosphodiesterases 1 and 2 (TDP1 and TDP2) with IC50 of 7.7 and 32 uM, respectively.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 664357-58-8
Chemical Name: JLT048
Formula: C22H15FN2O5
M.Wt: 406.37
Cat. No. Product name Field of application
DC73210 TH7528 TH7528 is a SAMHD1 inhibitor with IC50 of 4.5 μM/2.8 μM/2.6 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively.
DC73203 DI-87 DI-87 ((R)-DI-87) is a highly potent, specific, orally bioavailable deoxycytidine kinase (dCK) inhibitor with IC50 of 3.15 nM.
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DC44975 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
DC41008 Fludarabine triphosphate Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate, inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
DC7762 RX-3117 RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
DC76243 UnyLinker 12 TEA UnyLinker 12 TEA is a universal linker that can be used to synthesize oligoribonucleotides.
DC76242 Ribavirin 5'-monophosphate dilithium Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent.
DC76241 Pseudouridine 5'-OTBDPS Pseudouridine 5'-OTBDPS (5-(5-O-TBDPS-β-D-ribofuranosyl)uracil) is an intermediate of Pseudouridine. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
DC76240 N-Acetyl-2',3'-acetyl-guanosine N-Acetyl-2', 3'-Acetyl-Guanosine is a modified guanosine nucleoside.
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