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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC78727 | (R,S,S)-VH032-Me TFA |
(R,S,S)-VH032-Me TFA is an E3 ligase Ligand and can be used for synthesis of dTAGV-1 hydrochloride.
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| DC78692 | CRBN ligand-186 |
CRBN ligand-186 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
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| DC78682 | E3 ligase Ligand 77 |
E3 ligase Ligand 77 is a CRBN type E3 ubiquitin ligase ligand. E3 ligase Ligand 77 can be used for synthesizing PROTAC, such as PROTAC RET Degrader 1.
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| DC78659 | E3 ligase Ligand 75 |
E3 ligase Ligand 75 is an E3 ligase ligand. E3 ligase Ligand 75 can be used for synthesis PROTAC K-Ras Degrader-7.
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| DC78597 | Deoxy-thalidomide-OMe |
Deoxy-thalidomide-OMe is an E3 ligase ligand. Deoxy-thalidomide-OMe can be used for synthesis of PROTAC LRRK2 Degrader-4.
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| DC78572 | Brigatinib A |
Brigatinib A is an GID4 ligand. Brigatinib A can be used for synthesizing PROTAC BCR-ABL Degrader-2.
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| DC78498 | 6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole |
6-(2,4-Dioxopyrimidin-1-yl)-1-methylindole is an E3 ligase ligand used in the synthesis of the PROTAC Androgen receptor degrader-1.
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| DC78487 | XB2M54 |
XB2M54 is a selective XIAP antagonist. XB2M54 inhibits NOD2-mediated inflammatory signaling. XB2M54 is an E3 ligase ligand. XB2M54 can be used for synthesis of PROTAC ERα Degrader-1.
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| DC78218 | XIAP ligand 5 |
XIAP ligand 5 is a XIAP antagonist. XIAP ligand 5 is an E3 ligase ligand. XIAP ligand 5 can be used for synthesis of PROTAC GNE-1567.
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| DC78217 | CDK12-Cyclin K ligand-1 |
CDK12-Cyclin K ligand-1 is a ligand of PROTAC degrader that binds to the E3 ligase. CDK12-Cyclin K ligand-1 can be used in the synthesis of PROTAC degrader such as PP-C8.
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| DC78213 | (S,S,S)-VH032 |
(S,S,S)-VH032 is the ligand for E3 Ligase (VHL) that can be used for synthesis of PROTAC SGK3 degrader-2.
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| DC78212 | (R,S,R)-AHPC-Me-Ac |
(R,S,R)-AHPC-Me-Ac is an E3 ligase ligand used in the synthesis of the PROTAC SHP2 Protein degrader-2.
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| DC78208 | E3 ligase Ligand 68 |
E3 ligase Ligand 68 is an E3 ligase ligand that can be used in the synthesis of PROTACs, such as PROTAC ER Degrader-3.
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| DC78174 | JY-5 |
JY-5 is an E3 ligase ligand. JY-5 can be used for synthesis of PROTAC JY-21.
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| DC78067 | E3 ligase Ligand 66 |
E3 ligase Ligand 66 is an E3 ligase ligand that can be used to recruit IAP proteins. E3 ligase Ligand 66 can be linked to SARS-CoV-2 Mpro ligand 1 through a linker to form PROTAC BP-198.
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| DC47206 | Thalidomide-5-CH2-NH2 hydrochloride Featured |
Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
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| DC72888 | Z0933M Featured |
Z0933M is a potent S phase kinase-associated protein 1 (Skp1) inhibitor with Kd of 54 nM, potently inhibits Skp1-F-box protein-protein interactions with Ki value of 231 nM in FP-based in vitro competition assays.
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| DC12249 | E3 ligase Ligand 1 dihydrochloride |
E3 ligase Ligand 1 dihydrochloride is a Hippel-Landau (VHL) E3 ligase-binding moiety based on PROTAC technology.
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| DC47216 | Thalidomide-5,6-F Featured |
Thalidomide-5,6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-F can be connected to the ligand for protein by a linker to form PROTACs.
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| DC71103 | Pomalidomide-PEG4-COOH Featured |
Pomalidomide-PEG4-COOH is a E3 ligase ligand-linker conjugate. Pomalidomide-PEG4-COOH contains the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology (extracted from patent WO2017184995A1).
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| DC41134 | Thalidomide-5-OH Featured |
Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs.
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| DC11571 | E3 Ligase Ligand 3 Featured |
E3 ligase Ligand 3 is a ligand of E3 ligase, used in PROTAC technology.
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| DC42559 | Piperidine-GNE-049-N-Boc |
Piperidine-GNE-049-N-Boc is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP.
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| DC46257 | N-Boc-SBP-0636457-OH |
N-Boc-SBP-0636457-OH, a ligand for E3 ubiquitin ligase, is used in the recruitment of IAP E3 ligases. N-Boc-SBP-0636457-OH can be connected to the ligand for Bcl-xL by a linker to form PROTAC Bcl-xL degrader-1.
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| DC44854 | β-Naphthoflavone-CH2-Br |
β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1.
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| DC42462 | Lenalidomide-I |
Lenalidomide-I (Compound 72) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-I can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BET degrader QCA570.
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| DC71678 | (S,R,S)-AHPC-O-PEG1-propargyl |
(S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC.
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| DC50247 | Cereblon inhibitor 1 |
Cereblon inhibitor 1, an isoindoline derivative, is a cereblon E3 ubiquitin ligase modulating drug. Cereblon inhibitor 1 has the potential for cancer research.
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| DC39709 | Lenalidomide-Br Featured |
Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs.
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| DC11565 | E3 Ligase Ligand 2 Featured |
E3 ligase Ligand 2 is a Ligand for E3 Ligase used in PROTAC technology.
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